REZUL'TATY FARMAKODOPPLEROGRAFII KAVERNOZNYKh ARTERIY S ALPROSTADILOM

The results of the evaluation of 396 patients with complaints of erectile dysfunction (ED) are presented. Alprostadil was used for the pharmacological Doppler sonography of cavernous arteries. The test was assessed 15 minutes after intracavernosal injection of drug. The degree of erectile dysfunction was defined in accordance with the degree of penile tumescence and rigidity of the penis. Along with assessment of the effectiveness of alprostadil, the spectral characteristics of the cavernous artery blood flow were analyzed. Clinical result of intracavernous administration of alprostadil (degree of filling and rigidity of the penis) was most pronounced in young patients. The presence and type of risk factors did not significantly influence the clinical result of test. Clinical result of intracavernous administration of drug in patients with preserved sexual activity was significantly higher. Thus, application of 5 μg of alprostadil is an effective and safe method for evaluation of patients with ED of various origins and severity.

erection, erectile dysfunction, cavernous arteries, alprostadil