EFFEKTIVNOST' ADAPTIROVANNOY MOLOChNOY SMESI S PROBIOTIKAMI V PROFILAKTIKE KARIESA U DETEY RANNEGO VOZRASTA


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The immune system and resistance to diseases is largely dependent on human nutrition. In recent literature, there is convincing evidence of the influence of mucosal microbiota on mucosal immunity and as a consequence on the implementation of inflammation. It is also well know that dental disease is closely associated with the violation of oral microflora. The investigation of the state of dental biofilm and evaluation of secretory immunoglobulin A (sIgA) level against the background of use of adapted milk formulas with probiotics in children aged one year to four years were performed. The 53 children were under observation; milk formulas with probiotics were introduced in the diet in 27 children, and comparison group consisted of 26 children. Also, controlled hygiene lessons were conducted in both groups for 3 months. The study showed improvement in hygiene index in both groups, reduction of frequency of detection of representatives of cariogenic microorganisms in dental biofilms, and normalization of the sIgA level in saliva of children who received infant formula with probiotics.

Full Text

Restricted Access

References

  1. Бондаренко В.М. Молекулярно-клеточные механизмы терапевтического действия пробиотических препаратов // Фарматека 2010. № 2. С. 26-32.
  2. Воробьев С.В., Кириченко Д.А., Паленый А.И. Препараты Тиогамма и Мильгамма в терапии гастроинтестинальной формы автономной нейропатии при сахарном диабете типа 2 // Врач 2007. № 11. С. 27-30.
  3. Городецкий В.В. Лечение диабетической полиневропатии и других дистрофически-дегенеративных и воспалительных заболеваний периферической нервной системы метаболическими препаратами: методические рекомендации. М., 2004.
  4. Кисельникова Л.П., Вагеманс Н.В. Современные возможности профилактики кариеса зубов у детей раннего возраста. 2010.
  5. Нетребенко О.К. Обзор новых статей и материалов по механизмам действия и роли пробиотиков у детей (2007-2008). 2009.
  6. Парфенов А.И., Бондаренко В.М. Что нам дал вековой опыт познания симбионтной кишечной микрофлоры // Архив патологии 2012. № 2. С. 21-5.
  7. Lundell AG, Andersson K, Josefsson E, et al. Soluble CD14 and CD83 from human neonatal antigen-presenting cells are inducible by commensal bacteria and suppress human neonatal Th2 differentiation. Infect Immun 2007;75:4097-104.
  8. Guidelines for the Evaluation of Probiotics in Food. Report of a Joint FAO/WHO working group on guideliness for the evaluation of probiotics in food. London; Ontario, 2002.
  9. Guemonde M, Laitinen K, Salminen S, et al. Breast milk: a sourse of bifidobacteria for infant gut development and maturation? Neonatology 2007;92:64-6.
  10. Hinds K, Gregory J. National Diet and Nutrition Survey: children aged 1.5-4.5 years. Vol. 2. Report of the dental survey. London, Her Majesty's Stationery Office, 1995.
  11. Leeber S, Vanderleydes G, De Keersmaecker SC. Genes and molecules of lactobacillus supporting probiotic action. Microbiol Mol Biol Rev 2008;72:728-64.
  12. Saavedra J. Use of Probiotics in Pediatrics: Rationale, Mechanisms of Action, and Practical application. Nutr Clin Pract 2007;22: 351-65.
  13. Yli-Knuuttila, Snall J, Kari K, et al. Colonization of Lactobacillus rhamnosus GG in the oral cavity. Oral microbiology Immunology 2006; 21:129-31.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2013 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies