NOVYE VOZMOZhNOSTI TERAPII BOL'NYKh METASTATIChESKIM RAKOM MOLOChNOY ZhELEZY, POLUChAVShIKh RANEE ANTRATsIKLINI TAKSAN-SODERZhAShchUYu KhIMIOTERAPIYu: OBZOR LITERATURY I KLINIChESKIY SLUChAY


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Abstract

For a long time, anthracyclines and taxanes have occupied a prominent place in the treatment of metastatic breast cancer. However, at a certain stage of the disease the possibility of using these drugs are exhausted. Currently, we have the arsenal of other cytostatic agents having particular efficacy in the third and subsequent lines of therapy. However, until 2010 none of the drugs (or regimens) had proved efficacy in patients previously treated with anthracyclines and taxanes. Eribulin, a drug with a novel mechanism of action, demonstrating effectiveness and acceptable controlled toxicity, is really effective in third line of therapy for metastatic breast cancer.

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L. G Zhukova

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