TsENTRAL'NYY NESAKhARNYY DIABET: V ChEM SEKRET EFFEKTIVNOGO LEChENIYa?


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The article is devoted to the etiopathogenesis, clinical presentation and diagnosis of central diabetes insipidus. Pharmacological characteristics of the desmopressin are presented. The approaches to replacement therapy are described. Particular attention is given to the intranasal spray Vazomirin. The rapid onset of antidiuretic effect is emphasized. It is concluded that nasal spray is not only the most convenient but also cost-effective form of desmopressin. Its main advantages include high precision dosing, rapid achievement of effect and convenient form of release.

Full Text

Restricted Access

About the authors

E. V Biryukova

Email: lena@obsudim.ru

References

  1. Физиология водно-солевого обмена и почки / Под ред. Ю.В. Наточина. В сер. Основы современной физиологии. СПб. Наука. 1993. 576 с.
  2. Aoyagi T., Koshimizu T.A., Tanoue A. Vasopressin regulation of blood pressure and volume: findings from via receptor-deficient mice. Kidney Int. 2009; 76(10): 1035-92.
  3. Agre P., King L.S., Yasui M., et al. Aquaporin water channels-from atomic structure to clinical medicine. J. Physiol. 2002; 542: 3-16.
  4. Bankir L. Antidiuretic action of vasopressin: quantitative aspects and interaction between V1a and V2 receptor-mediated effects. Cardiovasc Res. 2001; 51: 372-390.
  5. Baylis P.H., Cheettham T. Diabetes insipidus. Arch. Dis. Child. 1998; 79: 84-9.
  6. Baylis P.H., Thompson C.J. Osmoregulation of vasopressin secretion and thirst in health and disease. Clin Endocrinol (Oxf) 1988; 29(5): 549-76.
  7. Ball S.G. Vasopressin and disorders of water balance: the physiology and pathophysiology. Ann Clin Biochem. 2007; 44: 417-31.
  8. Callreus T., Lundahl J., Hoglund P., Bengtsson P. Changes in gastrointestinal motility influence the absorption of desmopressin. Eur. J Clin Pharmacol. 1999; 55(4): 305-9.
  9. Carraro A., Fano M., Porcella E., Bernareggi V., Giusti M. Treatment of central diabetes insipidus using oral DDAVP. Comparison with intranasal treatment. Minerva Endocrinol. 1991; 16(3): 141-45.
  10. Clements J.A., Funder J.W. Arginine Vasopressin (AVP) and AVP-like immunoreactivity in peripheral tissues. Endocr. Rev.1986; 7: 449-60.
  11. David J.-L. Desmopressin and hemostasis. Regul. Pept. 1993; 45: 311-17.
  12. Durr J.A. Diabetes insipidus in pregnancy. Am J Kidney Dis 1987; 9: 276-83.
  13. Finley J.J., Konstam A., Udelson J.E. Arginine vasopressin antagonists for the treatment of heart failure and hyponatremia. circulation. 2008; 118: 410-21.
  14. Kim R.J., Malattia C., Allen M., et al. Vasopressin and desmopressin in central diabetes insipidus: adverse effects and clinical considerations. Pediatr Endocrinol Rev. 2004; 2(suppl 1): 115-23.
  15. Kozono D., Yasui M., King L.S., Agre P. Aquaporin water channels: atomic structure molecular dynamics meet clinical medicine. Clin. Invest. 2002; 109(11): 1395-99.
  16. Laczi F. Diabetes insipidus: etiology, diagnosis, and therapy. Orv Hetil 2002; 143(46): 2579-85.
  17. Maghnie M. Diabetes insipidus. Horm Res. 2003; 59: 142-54.
  18. Mendoza M.F., Cordenas T.H., Montero G.P., Bravo R.L. Desmopressin tablets in treatment of patients with central diabetes insipidus. Cir Ciruj. 2002; 70(2): 93-7.
  19. Nemergut E.C. Predictors of diabetes insipidus after transsphenoidal surgery: a review of 881 patients. J Neurosurg 2005; 103: 448-54.
  20. Nielsen S., Frokiaer J., Marples D. et al. Aquaporins in the kidney: from molecules to medicine. Physiol Rev. 2002; 82: 205-44.
  21. Pivonello R., De Bellis A., Faggiano A. et al. Central diabetes insipidus and autoimmunity: relationship between the occurrence of antibodies to arginine vasopressin-secreting cells and clinical, immunological, and radiological features in a large cohort of patients with central diabetes insipidus of known and unknown etiology. J Clin Endocrinol Metab. 2003; 88(4): 1629-36.
  22. Prager-Khoutorsky M., Bourque C.W. Osmosensation in vasopressin neurons: changing actin density to optimize function. Trends Neurosci. 2010; 33(2): 76-83.
  23. Robinson A.G., Verbalis J.G. The posterior pituitary. In Williams Textbook of Endocrinology; Philadelphia, 2003. Р. 281-329.
  24. Robertson G.L., Shelton R.L., Athar S. The osmoregulation of vasopressin. Kidney Int. 1976; 10(1): 25-37.
  25. Robertson G.L. Thirstand vasopressin function in normal and disordered states of water balance. J Lab Clin Med 1983; 101: 351-71.
  26. Sands J.M., Layton H.E. The physiology of urinary concentration: an update. Semin Nephrol. 2009; 29(3): 178-95.
  27. Tien R. MR imaging of the brain in patients with diabetes insipidus. Am J Neuroradiol 1991; 12: 533-42.
  28. Vande Walle J., Stockner M., Raes A., Nrgaard J.P. Desmopressin 30 years in clinical use: a safety review. Curr Drug Saf. 2007; 2(3): 232-38.
  29. Verbalis J.G. Diabetes insipidus. Rev Endocr Metab Disord. 2003; 4: 177-85.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2014 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies