KOGNITIVNYE NARUShENIYa PRI KhRONIChESKOY IShEMII GOLOVNOGO MOZGA


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Vascular brain lesions are one of the most frequent causes of cognitive impairment, especially in elderly and senile patients. Their severity is variable: from a minimum disorders of higher brain functions to dementia. Currently, the treatment of cognitive dysfunction in vascular cognitive impairment (VCI) includes the use of cholinesterase inhibitors and NMDA (N-methyl-D-aspartate) antagonists. Primary and secondary prevention of SKN is similar to the prevention of stroke [11]. Phenotropil is the one of the most promising drug for the treatment and prevention of the progression of cognitive impairment.

Full Text

Restricted Access

References

  1. Bowler J.V. Vascular cognitive impairment. Neurology Neurosurgery Psychiatry. 2005; 76(Suppl V): 35-44.
  2. Chui H.C., Victoroff J.I., Margolin D. Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer's Disease Diagnostic and Treatment Centers. Neurology. 1992; 42: 473-80.
  3. Erkinjunnti T., Inzitari D., Pantoni L. Research criteria for subcortical vascular dementia in clinical trials. Journal of Neural Transmission. Supplement. 2000; 59: 23-30
  4. Portet F., Ousset P.J. Mild cognitive impairment (MCI) in medical practice: a critical review of the concept and new diagnostic procedure. Report of the MCI Working Group of the European Consortium on Alzheimer's Disease. 2006. doi: 10.1136/jnnp.2005.085332. PMCID: PMC2077456
  5. Petersen R.C., Smith G.E., Waring S.C., et al. Mild cognitive impairment: clinical characterization and outcome. Archives Neurology. 1999; 56(3): 303-08.
  6. Grundman M., Petersen R.C., Ferris S.H., et al. Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials. Archives Neurology. 2004; 61(1): 59-66.
  7. Tabert M.H., Manly J.J., Liu X. Neuropsychological prediction of conversion to Alzheimer disease in patients with mild cognitive impairment. Archives General Psychiatry. 2006; 63(8): 916-24.
  8. Wentzel C., Rockwood K., MacKnight C. Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology. 2001; 57: 714-16.
  9. Rockwood K., Wentzel C., Hachinski V., et al. Prevalence and outcomes of vascular cognitive impairment. Vascular cognitive impairment investigators of the Canadian study of health and aging. Neurology. 2000; 54: 447-51.
  10. Geroldi C., Ferrucci L., Bandinelli S. Mild cognitive deterioration with subcortical features: prevalence, clinical characteristics, and association with cardiovascular risk factors in community-dwelling older persons (The InCHIANTI Study). J. American Geriatrics Society. 2003; 51(8): 1064-71.
  11. Levine D.A., Langa K.M. Vascular Cognitive Impairment: Disease Mechanisms and Therapeutic Implication; Neurotherapeutics. 2011; 8: 361-73.
  12. Ferri C.P., Prince M., Brayne C., et al. Global prevalence of dementia: Delphi consensus study. Lancet. 2005; 366: 2112-17.
  13. O'Brien J.T., Erkinjuntti T., Reisberg B., et al. Vascular cognitive impairment. Lancet. Neurol. 2003; 2: 89-98.
  14. Gorelick P.B., Scuteri A., Black S.E., et al. Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke. 2011; 42: 2672-713.
  15. Farooq M.U., Gorelick P.B. Vascular Cognitive Impairment. Cardiovascular disease and stroke. 2013; 15: 330.
  16. Rockwood K., et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005; 173: 489-95.
  17. Wentzel C., Rockwood K. Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology. 2001; 57(4): 714-16.
  18. Petersen R.C. Mild cognitive impairment: where are we? 2005 Alzheimer Dis Assoc Disord. 2005; 19(3): 166-69.
  19. Petersen R.C. Mild cognitive impairment as a diagnostic entity. J. Internal Medicine. 2004; 256: 183-94.
  20. Roman G.C., Tatemichi T.K., Erkinjuntti T. Vascular dementia: diagnostic criteria for research studies: report of the NINDSAIREN International Workshop. Neurology. 1993; 43: 250-60.
  21. Pedelty L., Nyenhuis D.L. Vascular Cognitive Impairment Current Treatment Options in Cardiovascular Medicine. 2006; 8: 243-50.
  22. Wade J., Hachinski V. Revised ischemic score for diagnosing multi-infarct dementia. J. Clin. Psychiatry. 1986; 47: 437-38.
  23. Nyenhuis D., Gorelick P.B. Vascular dementia: a contemporary review of epidemiology, diagnosis, prevention, and treatment. J. American Geriatrics Society. 1998; 46: 1437-48.
  24. Starkstein S.E., Sabe S., Vasquez S., et al. Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer's disease. Stroke. 1996; 7: 408-14.
  25. Erkinjuntti T., Gauthier S. The Concept of Vascular Cognitive Impairment Dementia in Clinical Practice. Frontiers in Human Neuroscience. 2009; 24: 79-85.
  26. Gorelick P.B. Risk factors for dementia and Alzheimer's disease. Stroke. 2004; 35(11 suppl 1): 2620-22.
  27. Caplan L.R., Schmahmann J.D., Kase C.S., et al. Caudate infarcts. Archives Neurology. 1990; 51: 133-43.
  28. Anoni J.M., Khateb A., Gramingna S. Chronic cognitive impairment following laterothalamic tract infarcts: a study of 9 cases. Archives Neurology 2003; 60: 1439-43.
  29. Auchus A., Chen C.P., Sodagar S.N., et al. Single stroke dementia: insights from 12 cases in Singapore. J. Neurology Science. 2002; 203-204: 85-9.
  30. Benisty S., Gouw A.A., Porcher R. on behalf of the LADIS Study group. Location of lacunar infarcts correlates with cognition in a sample of non-disabled subjects with age-related white-matter changes: the LADIS study. J. Neurology Neurosurgery Psychiatry. 2009; 80: 478-83.
  31. Barba R., Martinez-Espinosa S., Rodriguez-Garcia E., Pondal M. Poststroke dementia: clinical features and risk factors. Stroke. 2000; 31: 1494-501.
  32. Henon H., Durieu, I., Guerouaou D., et al. Poststroke dementia: incidence and relationship to prestrike cognitive decline. Neurology. 2001; 57(12): 16-22.
  33. Englund E. Neuropathology of white matter lesions on vascular cognitive impairment. Cerebrovascular Diseases. 2002; 13: 11-15.
  34. Caplan L.R. Binswanger' disease-revisited. Neurology. 1995; 45: 626-33.
  35. Rosenberg G.A. Inflammation and white matter damage in vascular cognitive impairment. Stroke. 2009; 40: S20-23.
  36. Adair J.C., Charlie J., Dencoff J.E., et al. Measurement of gelatinase B (MMP-9) in the cerebrospinal fluid of patients with vascular dementia and Alzheimer disease. Stroke. 2004; 35: e159-62.
  37. Simpson J.E., Fernando M.S., Clark L. White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and Current Atherosclerosis Reports. 2013; 15: 330 Page 5 of 7, 330.
  38. Weller R.O., Boche D., Nicoll J.A. Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy. Acta Neuropathologica. 2009; 118: 87-102.
  39. Gurol M.E., Irizarry M.C., Smith E.E., et al. Plasma beta-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy. Neurology. 2006; 66: 23-9.
  40. Sim F.J., Zhao C., Penderis J., et al. The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J. Neuroscience. 2002; 22: 2451-59.
  41. Louissaint Jr. A., Rao S., Leventhal C., et al. Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron. 2002; 34: 945-60.
  42. Yamamoto H., Watanabe T., Miyazaki A., et al. High prevalence of Chlamydia pneumoniae antibodies and increased high-sensitive C-reactive protein in patients J. Neurology Neurosurgery Psychiatry. 2006; 77(6): 714-18.
  43. Utermann G. Apolipoprotein E polymorphism in health and disease. American Heart J. 1987; 113(2 Part 2): 433-40.
  44. Mahley R.W., Weisgraber K.H., Huang Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology,including Alzheimeer's disease. Proceedings of the National Academy of Sciences USA. 2006; 103: 5644.
  45. Hebert R., Lindsay J., Verreault R., Rockwood K., Hill G., Dubois M.F. Vascular dementia: incidence and risk factors in the Canadian study of health and aging. Stroke. 2000; 31: 1487-93.
  46. Baum L., Lam L.C., Kwok T., et al. Apolipoprotein E epsilon4 allele is associated with vascular dementia. Dementia Geriatric Cognitive Disorders. 2006; 22: 301-305.
  47. Kuller L.H., Lopez O.L., Newman A., et al. Risk factors for dementia in the cardiovascular health cognition study. Neuroepidemiology. 2003; 22: 13-22.
  48. Rowan E., Morris C.M., Stephens S., et al. Impact of hypertension and apolipoprotein E4 on poststroke cognition in subjects > 75 years of age. Stroke. 2005; 36: 1864-68.
  49. Dichgans M. Cognition in CADASIL. Stroke. 2009; 40: S45-7.
  50. Gasparovic C., Prestopnik J., Thompson J., et al. 1H-MR spectroscopy metabolite levels correlate with executive function in vascular cognitive impairment. J. Neurology Neurosurgery Psychiatry. 2013.
  51. Кадыков А.С., Манвелов Л.С., Шахпаронова Н.В. Хронические сосудистые заболевания головного мозга. Дисциркуляторная энцефалопатия. М., 2013. 232 с.
  52. Амчеславская Е.В., Красноперов Е.Н., Белопасова А.В. Изучение эффективности и безопасности применения Фенотропила у больных пожилого возраста с хронической ишемией головного мозга / I Всероссийский конгресс молодых ученых в области медицины и биологии. Сборник научных трудов / Под ред. В.И. Ахапкиной. М., 2009. С. 10-5.
  53. Верлан Н.В., Кулинский В.И., Колесниченко Л.С. и др. Изучение эффективности и безопасности применения Фенотропила у больных с дисциркуляторной энцефалопатией II стадии / 1 Всероссийский конгресс молодых ученых в области медицины и биологии. Сборник научных трудов / Под ред. В.И. Ахапкиной. М., 2009. С. 21-3.
  54. Чичановская Л.В., Бардукова Е.А. Изучение эффективности Фенотропила при хронической ишемии головного мозга / I Всероссийский конгресс молодых ученых в области медицины и биологии. Сборник научных трудов / Под ред. В.И. Ахапкиной. М., 2009. С. 24-9.
  55. Gorelik P.B., Bowler J.V. Advances in vascular cognitive impairment. Stroke. 2010; 41: 2: 93-8.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2014 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies