Sostoyanie verkhnikh otdelov pishchevaritel'nogo trakta i ratsional'nyy vybor antisekretornoy terapii u patsientov starcheskogo vozrasta


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Abstract

Complaints, medical history, data for physical examination and endoscopy of the upper gastrointestinal tract in 356 elderly patients were analyzed. The analysis has revealed the prevalence of erosive and ulcerative lesions of the upper gastrointestinal tract as general pathology, an imbalance between the severity of clinical manifestations and endoscopic changes, and the use of large amounts of drugs due to the presence of concomitant pathology of internal organs, especially coronary artery disease and arterial hypertension. The main group of drugs used to treat acid-related diseases is the proton pump inhibitors (PPIs). As in the older age groups, long-term regular PPI therapy is usually required, it is desirable to use the drug with the least amount of drug-drug interactions. Pantoprazole meets this requirement and surpass other PPIs on in this property.

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