Glyukokortikosteroidnye gormony - «zolotoy» standart v lechenii bol'nykh bronkhial'noy astmoy


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

This paper reviews the role of glucocorticoids in the treatment of patients with bronchial asthma. Cellular and molecular mechanisms of anti-inflammatory action of glucocorticoids are discussed. Systemic and inhaled corticosteroids are presented as a means of achieving and maintaining asthma control. A variety of corticosteroid medications for asthma, as well as devices for delivery of inhaled corticosteroid formulations are compared. Efficient regimens of systemic and inhaled corticosteroids administration are presented.

Full Text

Restricted Access

About the authors

V. I Trofimov

Email: trofvi@mail.ru

References

  1. Global Initiative for Asthma. Global strategy for Asthma Management and Prevention. Revised. 2014. www.ginasthma.org
  2. Barnes P.J., Adcock J.M. How Do Corticosteroids Work in Asthma? Ann. Intern. Med. 2003;139:359-70.
  3. Schwiebert L.M., Stellato C, Schleimer R.P. The epithelium as a target of glucocorticoid action in the treatment of Asthma. Am. J. Respir. Crit. Care Med. 1996;154: 16-20.
  4. Barnes P.J. Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease. J. Allergy Clin. Immunol. 2013;131:636-45.
  5. Hubner M., Hochhaus G., Derendorf H. Comparative pharmacology, bioavailability, pharmacokinetics, and pharmacodynamics of inhaled glucocorticoids. Immunol. Allergy Clin. North. Am. 2005;25:469-88.
  6. Ненашева Н.М. Безопасность ингаляционных глюкокортикостероидов в терапии бронхиальной астмы. Пульмонология. 2014;3:113-20.
  7. Padden J., Sconer D., Hochhaus G. Pharmacokinetics, and pharmacodynamics of inhaled glucocorticoids. J. Asthma. 2006;45(1):13-24.
  8. Трофимов В.И. Циклесонид в лечении больных бронхиальной астмой. Медицинский твет. 2014;16:32-4.
  9. Бернс П., Годфри С. Бронхиальная астма. М.: Бином, 2003. 125 с.
  10. Ahmet A., Kim H., Spie S. Adrenal suppression: a practical guide to the screening and management of this under-recognise complication of inhaled corticosteroid therapy. Allergy Asthma Clin. Immunol. 2013;7:13. doi: 10.1186/17101492-7-13.
  11. Buehring B., Viswanthem R., Binkley N., Busse W. Glukocorticoid-indused osteoporosis: an apdate on effects and management. J. Allergy Clin. Immunol. 2013;132:1019-30.
  12. Ferguson A.S., van Bever H.P., Teper A.M., Lasytsya O., Goldfrad C.H., Whitehead P.J. A comparison of the relative growth velocities with budesonide and fluticasonr propionate in children with asthma. Respir. Med. 2007;101:118-29.
  13. Kelly H.W., Nelson H.S. Potential adverse effects of the inhaled corticosteroids. Allergy Clin. Immunol. 2003;112(3):469-68.
  14. Keiser H. Praxis der Cortisontherapie. Urban und Schwarzenberg, 1992. 96 p.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2015 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies