Klinicheskiy sluchay uspeshnogo lecheniya erilibulinom metastaticheskogo raka molochnoy zhelezy


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Currently, it is possible to significantly prolong life of patients with breast cancer by alternation of the various schemes of cytotoxic, hormonal and targeted therapies defined in accordance with the biological subtype of breast cancer (BC). Choice of cytostatics in case of the ineffectiveness of anthracyclines and taxanes is very difficult. Today, however, there is a new drug in the arsenal of oncologists -eribulin, which has many indisputable advantages, and the main advantage is the efficiency in anthracycline-taxane-resistant metastatic breast cancer, that allows to significantly increase the life expectancy of patients with preservation of quality of life.

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  1. Cardoso F., Harbeck N., Fallowfield L., Kyriakides S., Senkus E.; ESMO Guidelines Working Group. Locally recurrent or metastatic breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 2012;23(7):11-9.
  2. International Agency for Research on Cancer. Europe - Most frequent cancers in women 2012. http://eco.iarc.fr/EUCAN/Country. aspx?ISOCountryCd=968.
  3. Kaprin A.D. Moscow Scientific Oncology Institute of PA Gertzen Ministry of Health RF. 2013.
  4. Autier P., Boniol M., Gavin A., Vatten L.J. Breast cancer mortality in neighbouring European countries with different levels of screening but similar access to treatment: trend analysis of WHO mortality database. BMJ. 2010;341:e3620.
  5. Жукова Л.Г. Антиангиогенная терапия при раке молочной железы с тройным негативным фенотипом. Газета общества онкологов-химиотерапевтов. 2013;4:4-7.
  6. Morris P.G. Advances in therapy: eribulin improves survival for metastatic breast cancer. Anti-cancer Drugs. 2010;21:885-89.
  7. Семиглазов В.Ф. Значение прогностических и предсказывающих факторов при выборе лечения у больных метастатическим раком молочной железы. Практическая Онкология. 2000;2:26-30.
  8. Sledge G.W., Rugo H.S., Burstein H.J. The role of angiogenesis inhibition in the treatment of breast cancer. Clin. Adv. Hematol. Oncol. 2011;9( 11, Suppl. 25):1-16.
  9. Chia S.K., Speers C.H., D'Yachkova Y., Kang A., Malfair-Taylor S., Barnett J., Coldman A., Gelmon K.A., O'reilly S.E., Olivotto I.A. The impact of new Chemotherapeutic and hormone agents on survival in a population-based cohort of women with metastatic breast cancer. Cancer. 2007;110:973 - 79.
  10. Twelves C., Cortes J., Vahdat L., Olivo M., He Y., Kaufman P.A., Awada A. Efficacy of eribulin in women with breast cancer: a pooled analysis of two phase 3 studies. Breast. Cancer Res. Treat. 2014;148(3):553-61.
  11. Жукова Л.Г., Окружнова М.А., Часовни-кова Е.О. Эрибулин в лечении метастатического рака молочной железы
  12. Dear R.F., McGeechan K., Jenkins M.C., Barratt A., Tattersall M.H., Wilcken N. Combination versus sequential single agent chemotherapy for metastatic breast cancer. Cochrane Database Syst. Rev. 2013;12:CD008792.
  13. Andreopoulou E., Sparano J.A. Chemotherapy in patients with anthracycline- and taxanepretreated metastatic breast cancer: an overview. Curr. Breast. Cancer. Rep. 2013;5:42-50.
  14. Lin N.U., Burstein H.J. EMBRACE, eribulin, and new realities of advanced breast cancer. Lancet. 2011;377:878-80.
  15. Rivera E. Management of metastatic breast cancer: monotherapy options for patients resistant to anthracyclines and taxanes. Am. J. Clin. Oncol. 2010;33(2):176-85.
  16. Murphy C.G., Seidman A.D. Evolving approaches to metastatic breast cancer previously treated with anthracyclines and taxanes. Clin. Breast. Cancer. 2009;9(2):58-65.
  17. Cardoso F., Senkus- Konefka E., Fallowfield L., Costa A., Castiglione M.; ESMO Guidelines Working Group.Locally recurrent or metastatic breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Onc. 2010;21(5):15-9.
  18. Gonzalez-Angulo A.M., Morales-Vasquez F., Hortobagyi G.N. Overview of resistance to systemic therapy in patients with breast cancer. Adv. Exp. Med. Biol. 2007;608:1-22.
  19. Colozza M., de Azambuja E., Personeni N., Lebrun F., Piccart M.J., Cardoso F. Achievements in systemic therapies in the pregenomic era in metastatic breast cancer. Oncologist. 2007;12:253-70.
  20. Cortes J., OShaughnessy J., Loesch D., Blum J.L., Vahdat L.T., Petrakova K., Chollet P., Manikas A., Diеras V., Delozier T., Vladimirov V., Cardoso F., Koh H., Bougnoux P., Dutcus C.E., Seegobin S., Mir D., Meneses N., Wanders J., Twelves C.; EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389) investigators. Eribulin monotherapy versus treatment of physicians choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomized study. Lancet. 2011;377:914-23.
  21. Beusterien K., Grinspan T., Brufsky A., Visovsky C. Patient preferences for chemotherapies used in breast cancer. ASCO. 2011:abst e19667.
  22. Hamel E. Natural products which interact with tubulin in the vinca domain: maytansine, rhizoxin, phomopsin A, dolastatins 10 and 15 and halichondrin B. Pharmacol. Ther. 1992;55:31-51.
  23. Towle M.J., Salvato K.A., Budrow J., Wels B.F., Kuznetsov G., Aalfs K.K., Welsh S., Zheng W., Seletsky B.M., Palme M.H., Habgood G.J., Singer L.A., Dipietro L.V., Wang Y., Chen J.J., Quincy D.A., Davis A., Yoshimatsu K., Kishi Y., Yu M.J., Littlefield B.A. In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B. Cancer Res. 2001;61:1013-21.
  24. Jordan M.A., Kamath K.,Manna T.,Okouneva T., Miller H.P., Davis C., Littlefield B.A., Wilson L. The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth. Mol. Cancer. Ther. 2005;4:1086-95.
  25. Kuznetsov G., Towle M.J., Cheng H., Kawamura T., TenDyke K., Liu D., Kishi Y., Yu M.J., Littlefield B.A. Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389. Cancer. Res. 2004;64:5760-6.
  26. Okouneva T., Azarenko O., Wilson L., Littlefield B.A., Jordan M.A. Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase. Mol. Cancer. Ther. 2008;7:2003-11.
  27. Smith J.A., Wilson L., Azarenko O., Zhu X., Lewis B.M., Littlefield B.A., Jordan M.A. Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability. Biochemistry. 2010;49:1331 -37.
  28. Wozniak K.M., Lapidus R.G., Wu Y. Comparison of neuropathy-inducing effects of eribulin versus paclitaxel in mice. Proc. Am. Assoc. Cancer. Res. 2010;51:4438.
  29. Kuznetsov G., TenDyke K., Yu M.J.,Littlefield B.A. Antiproliferative effects of halichondrin B analog eribulin mesylate (E7389) against paclitaxel-resistant human cancer cells in vitro. Proc. Am. Assoc. Cancer. Res. 2007;48:275:C58.
  30. Kuznetsov G., TenDyke K., Yu M., Littlefield B. Antiproliferative effects of halichondrin B analog eribulin mesylate (E7389) against paclitaxel-resistant human cancer cells in vitro. AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, San Francisco, CA. 2007:C58.
  31. Goel S., Mita A.C., Mita M., Rowinsky E.K., Chu Q.S., Wong N., Desjardins C., Fang F., Jansen M., Shuster D.E., Mani S., Takimoto C.H. A Phase I study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced solid tumors. Clin. Cancer. Res. 2009;15:4207-12.
  32. Tan A.R., Rubin E.H., Walton D.C., Shuster D.E., Wong Y.N., Fang F., Ashworth S., Rosen L.S. Phase I study of eribulin mesylate (E7389) administered once every 21 days in patients with advanced solid tumors. Clin. Cancer. Res. 2009;15:4213-8.
  33. Vahdat L.T., Pruitt B., Fabian C.J., Rivera R.R., Smith D.A., Tan-Chiu E., Wright J., Tan A.R., Dacosta N.A., Chuang E., Smith J., O'Shaughnessy J., Shuster D.E., Meneses N.L., Chandrawansa K., Fang F., Cole P.E., Ashworth S., Blum J.L. Phase II study of eribulin mesylate, a halichondrin B analog, in patients with meta static breast cancer previously treated with an anthracycline and a taxane. J. Clin. Oncol. 2009;27:2954-61.
  34. Cortes J., Vahdat L., Blum J.L., Twelves C., Campone M., Roche H., Bachelot T., Awada A., Paridaens R., Goncalves A., Shuster D.E., Wanders J., Fang F., Gurnani R., Richmond E., Cole P.E., Ashworth S., Allison M.A. Phase II study of the halichondrin B analog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane, and capecitabine. J. Clin. Oncol. 2010;28: 3922-28.

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