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Low back pain (LBP) is a common clinical syndrome characterized by frequent recurrence associated with the risk of disability and significant material costs. Serious problems of treating patients with LBP include formation of chronic pain and the risk of complications of therapy. The possibility of use of diacerein in patients with LBP is of considerable interest; clinical effects of this drug are realized primarily by inhibiting the activity of interleukin-1. The results of experimental and clinical studies on the effectiveness and tolerability of the drug in patients with articular pathology are discussed.

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