ROL' ALLEL'NYKh VARIANTOV GENOV SVERTYVANIYa KROVI V SKOROSTI PROGRESSIROVANIYa FIBROZA PRI KhRONIChESKIKh ZABOLEVANIYaKh PEChENI


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Resumo

The rate of progression of fibrosis in different patients varies and depends on many factors, such as race, gender, age of ingress of infection, genotype, presence of concomitant diseases, bad habits, etc. Currently, the most urgent task is the identification of specific genetic factors of progression of fibrosis that will help to determine the prognosis and tactics of management for these patients. The review describes the available literature data on the effect of polymorphisms of thrombophilia and platelet receptors genes on the course and prognosis of chronic liver diseases.

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