Opyt primeneniya shampunya klobetazola propionata pri psoriaze volosistoy chasti golovy


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Abstract

The efficacy and safety of the use of 0.05% clobetasol propionate shampoo in patients with psoriasis of the scalp in the acute phase. The effectiveness of the therapy was evaluated in 60 adult patients on 0, 7, 14, 21, and 28th days using a dynamic calculation of mPASI, TSS indices, and the intensity of itching. The safety of therapy was assessed by the frequency of side effects. It was shown that a daily 15-minute application of clobetasol propionate shampoo for 28 days promotes regression of psoriatic rash of the scalp, decrease of lesion area, as evidenced by a statistically significant change of dermatological mPASI, TSS indices and itching. Distinct therapeutic effect and absence of side effects have contributed to the high adherence to topical therapy of patients with psoriasis of the scalp.

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