THE ROLE OF ACUTE INTESTINAL INFECTIONS OF VIRAL ETIOLOGY IN THE DEVELOPMENT OF FUNCTIONAL PATHOLOGY OF THE GASTROINTESTINAL TRACT IN CHILDREN


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Abstract

The article presents the results of studies of the functional disorders of the gastrointestinal tract (GIT), and changes in intestinal microbiota in 120 children who had acute intestinal infection caused by rotaviruses and noroviruses. It was shown that functional gastrointestinal pathology realized at 18.3% of convalescents after viral gastroenteritis. Changes of microbiota in viral gastroenteritis of different etiologies have a number of specific features: reducing the quantitative content of Faecalibacterium prausnitzii, raising of Bacteroides thetaiotaomicrion in rotavirus infection, pronounced inhibition of growth of Lactobacillus spp. and Bifidobacterium spp., the excessive growth of opportunistic bacteria in norovirus infection.

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About the authors

K. D Ermolenko

FSBI Scientific Research Institute of Children's Infections FMBA; SRI of Epidemiology and Microbiology n.a. Pasteur

Email: ermolenko.kd@yandex.ru
postgraduate student; Researcher at the department of identification of pathogens

N. V Gonchar

FSBI Scientific Research Institute of Children's Infections FMBA; Northwestern State Medical University n.a. I.I. Mechnikov

E. I Ermolenko

FSBIS Institute of Experimental Medicine; St. Petersburg State University

M. A Suvorova

FSBIS Institute of Experimental Medicine

E. A Tarasova

FSBIS Institute of Experimental Medicine

M. P Kotyleva

FSBIS Institute of Experimental Medicine

Yu. V Lobzin

FSBI Scientific Research Institute of Children's Infections FMBA; Northwestern State Medical University n.a. I.I. Mechnikov

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