详细
The article presents the results of a comparative clinical study conducted for a year among two groups of patients (48 and 47 women, respectively) aged over 50 years with extra-articular fractures of the proximal femur against the background of severe involutive osteoporosis (OP); patients received surgical treatment (osteosynthesis using PFN fixators) or combined surgical and antiosteoporotic treatment with two different drug regimens. It was established that the severe OP with X-ray densitometry T-test values below the threshold level (less than -3,3 SD) can be considered as a risk factor for osteosynthesis complications associated with the implant, and risk is increased by 23.6 times. In such patients, drug therapy of involutive OP using only calcium and vitamin D3 is useful, but does not prevent a significant reduction in bone mineral density after 6 months after the surgery. Antiosteoporotic therapy with the addition of strontium ranelate in calcium and vitamin D allows almost stabilize the rate of bone mineral density by the deadline at the level marked in the period of implementation of the osteosynthesis operation. Complex treatment of patients with extra-articular fractures of the proximal femur on the background of involutive OP with osteosynthesis using PFN fixators and 6-month therapy with calcium, vitamin D3 and strontium ranelate using tested scheme provides better functional outcomes one year after surgery compared with similar groups of patients, receiving only calcium and vitamin D3, and not receiving specific antiosteoporotic therapy.
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