ENDOSONOGRAPHY OF LUNGS AND MEDIASTINUM IN ONCOLOGY: FEATURES OF VERIFICATION OF THE DIAGNOSIS


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The study was aimed to the assessment of the feasibility of the use of endobronchial ultrasound (EBUS-TBNA) for the diagnosis of peribronchial neoplasms of lungs and mediastinal organs. The examination was conducted using convex ultrasound bronchoscope or ultrasonic mini-sensors with subsequent fine-needle aspiration biopsy and biopsy with «Essen» forceps. The use of EBUS-TBNA allowed to make the correct diagnosis in 152 (83.0%) of 183 cases. Mini-sensor and convex bronchoscope had similar performance: 84.6 and 81.7%, respectively (p=0.89, χ2 test). Depending on the location, the best diagnostic results were obtained regarding to 7th zone of lymph nodes - 35 (94.6%) of 37 cases; 2R zone was the most difficult area - 8 of 16 cases (50%, p=0.003, X2 test). 3 (1.6%) patients experienced mild bleeding to the extent of 50 ml during the procedure. 2 (1.1%) patients experienced slight subcutaneous emphysema in the neck during the first days after a biopsy of 2nd zone lymph nodes using forceps. Deaths were not registered. It is emphasized that EBUS-TBNA is effective method of sampling of peribronchial lungs and mediastinal tumors for cytological and histological examination, and it has advantages over other methods of verification of such tumors.

Full Text

Restricted Access

About the authors

V. N Korolyov

Email: VL_korolyov@mail.iu
LLC "EVIMED" PhD, endoscopist, Deputy Director Chelyabinsk

D. V Gogoleva

SBHCI "Chelyabinsk Pathologoanatomic Bureau" Chelyabinsk

E. V Malakhova

SBHCI "Chelyabinsk Pathologoanatomic Bureau" Chelyabinsk

O. A Kurnosova

MBHCI City Clinical Hospital № 6 Chelyabinsk

References

  1. Давыдов М.И., Мачаладзе З.О., Полоцкий Б.Е. и др. Мезенхимальные опухоли средостения (обзор литературы). Сибирский онкологический журнал. 2008;1:64-74.
  2. Канаев С.В. Принципы и обоснования химиолучевого лечения злокачественных опухолей. Практическая онкология. 2008;1:1-8.
  3. Мачаладзе З.О. Опухоли средостения (дифференциальная диагностика и лечение). Дисс. докт. мед. наук. М., 2008. 50 с.
  4. Синюкова Г.Т., Гудилина Е.А. Ультразвуковая диагностика новообразований плевры и средостения. VII российская онкологическая конференция. 25-27 ноября 2003 г. РОНЦ РАМН им. Н.Н. Блохина, Москва.
  5. Becker H. Endobronchialer Ultraschall-Eine neue Perspektive in der Bronchologie. Ultraschall. Med. 1996;17:106-12.
  6. Bolliger C.T., Herth F.J.F., Mayo P.H., Miyazawa Т. Clinical Chest Ultrasound: From the ICU to the Bronchoscopy Suite. Prog. Respir. Res. 2009;37:153-59.
  7. Brown J.M., Giaccia A.J. The unique physiology of solid tumors: opportunities (and problem) for cancer therapy. Cancer Res. 1998;58:1408-16.
  8. Coulibaly B., Bouvier C., Payan M.J., Thomas P. Recurrent dedifferentiated liposarcoma of mediastinum involving lung and pleura. Interact. Cardiovasc. Thorac. Surg. 2009;9:741-2.
  9. Hurtur T., Hanrath P. Endobronchial sonography: feasibility and preliminary results. Thorax. 1992;47:565-67.
  10. Kurimoto N., Murayama M., Yoshioka S., Nishisaka T., Inai K., Dohi K. Assessment of usefulness of endobronchial ultrasonography in determination of depth of tracheobronchial tumor invasion. Chest. 1999;115:1500-506.
  11. Kurimoto N., Fielding D.I.K., Musani A.I. Endobronchial Ultrasonography. Wiley-Blackwell, 2011. 166 p.
  12. Macchiarini P., Ostertag H. Uncommon primary mediastinal tumours. Lancet Oncol. 2004;5(2):107-18.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2016 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies