Wilson’s disease: modern methods of diagnosis and treatment


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详细

The article presents data on the etiology, pathogenesis, classification, clinical manifestation and treatment of Wilson’s disease (WD; hepatolenticular degeneration). It is emphasized that the main method of treatment of WD is the use of copper-depleting agents (chelation therapy) and adherence to a strict diet with a reduced amount of copper in the food. The complex case of authors’ clinical observation of WD in 51-year-old man is described. This case illustrates one of the clinical variants of WD characterized by a latent course (up to 20 years), decompensated liver cirrhosis and development of severe neurological symptoms against the background of low adherence to the treatment.

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作者简介

T. Khaymenova

SBHCI «Moscow Clinical Research and Practical Center» of Moscow Healthcare Department

E. Vinnitskaya

SBHCI «Moscow Clinical Research and Practical Center» of Moscow Healthcare Department

Email: evinn@mail.ru
MD

I. Bakulin

FSBEI HE «North-Western State Medical University n.a. I.I. Mechnikov» of RMH

T. Shkurko

SBI «SRI of Public Health Organization and Medical Management of Moscow Healthcare Department»

A. Nikitina

SBHCI «Moscow Clinical Research and Practical Center» of Moscow Healthcare Department

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