POSTSTROKE CEREBELLARCOGNITIVE AFFECTIVE SYNDROME


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Abstract

Cerebellar infarctions are a relatively rare pathology: 1.5-2.3% of acute cerebrovascular disiorders. Topographical classification of cerebellar infarctions is presented; infarct-induced disorders of its functions are considered. For many years, the cerebellum was considered as the key structure of the brain in the regulation of motor functions. Now it is established that it plays a role in the realization of other functions of the body (psychoemotional, vegetative, etc.). In recent years, experimental studies on the role of the cerebellum in the realization of cognitive functions have been carried out. The spectrum of behavioral and cognitive impairments resulting from cerebellar stroke is defined as a cerebellar cognitive affective syndrome. This syndrome includes a violation of executive functions and is characterized by perseverations, absent-mindedness or inattention, visual-spatial disturbances, difficulties in speech production, and personality changes. At the same time, remote episodic and semantic memory is preserved, and the learning ability is only slightly affected. The etiotropic and pathogenetic therapy of post-stroke CI is primarily aimed at the underlying pathological processes causing cerebrovascular insufficiency such as arterial hypertension, atherosclerosis, heart diseases, etc. For the improvement of cognitive functions, a wide range of nootropic agents are used. They can be divided into the main groups: drugs with neurometabolic action, drugs with neurotrophic action, drugs that affect certain neurotransmitter systems, and vasoactive drugs.

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About the authors

E. Yu Solovieva

FSBEI HE RNSMU n.a. N.I. Pirogov of RMH

Email: ellesolovieva@yandex.ru
Department of Neurology FFPE

I. V Tsoy

FSBEI HE RNSMU n.a. N.I. Pirogov of RMH

Department of Neurology FFPE

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