THE USE OF METHYLPREDNISOLONE ACEPONATE IN THE COMPLEX THERAPY OF ATOPIC DERMATITIS IN CHILDREN


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Abstract

The article presents an analysis of literature data on the experience of the use of methylprednisolone aceponate (Advantan, BAYER) in the treatment of children with atopic dermatitis. The study was aimed to the evaluation of the efficacy and safety of methylprednisolone aceponate in the treatment of children with atopic dermatitis. In different countries, studies on the use of various dosage forms of this drug have been conducted. The efficacy and safety of methylprednisolone aceponate is shown.

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About the authors

A. A Tsykin

FSBEI HE RNSMU n.a. N.I. Pirogov of RMH

Department of Skin Diseases and Cosmetology FAPE Moscow

I. V Khamaganova

FSBEI HE RNSMU n.a. N.I. Pirogov of RMH

Email: irina.khamaganova@gmail.com
MD, Professor at the Department of Skin Diseases and Cosmetology FAPE Moscow

References

  1. Федеральные клинические рекомендации по диагностике и лечению атопического дерматита, утв. Президиумом РААКИ 23 декабря 2013 г.
  2. Sidbury R., Khorsand K. Evolving Concepts in Atopic Dermatitis. Curr. Allergy Asthma Rep. 2017;17(7):42.
  3. Grey K.R., Hook K.P., Polcari I.C., Maguiness S.M. Perceptions and Practices Regarding Atopic Dermatitis: A Survey. Pediatr. Dermatol. 2017 May 25. doi: 10.1111/pde.13162. [Epub ahead of print].
  4. Andersen R.M., Thyssen J.P., Maibach H.l. Qualitative vs. quantitative atopic dermatitis criteria- in historical and present perspectives. J. Eur. Acad. Dermatol. Venereol. 2016;30(4):604-18.
  5. Hanifin J.M., Rajka G. Diagnostic features of atopic dermatitis. Acta Derm. Venereol. 1980;92(l):44-7.
  6. Кулагин В.И., Хамаганова И.В., Войнич З.В., Шекрота А.Г Опыт применения мази «Адвантан» в детской дерматологической практике. Вест. дерматологии и венерологии. 2000;6:50.
  7. Blume-Peytavi U., Metz M. Atopic dermatitis in children: management of pruritis. J. Eur. Acad. Dermatol. Venerol. 2012;26(6):2-8.
  8. Jiráková A., Rob F., Sečníková Z., Koblová K., Džambová M., Rajská L., Göpfertová D., Pellacani G., Maly M., Lotti T., Hercogová J. Topical corticosteroids but not calcineurin inhibitors induced atrophy after four weeks. J. Biol. Regul. Homeost. Agents. 2015;29(3):701-6.
  9. Yoon N.Y, Jung My., Kim D.H., Lee H.J., Choi E.H. Topical glucocorticoid or pimecrolimus treatment suppresses thymic stromal lymphopoietin-related allergic inflammatory mechanism in an oxazolone-induced atopic dermatitis murine model. Arch. Dermatol. Res. 2015; 307(7):569-81.
  10. Bieber T., Vick K., Fölster-Holst R., Belloni-Fortina A., Städtler G., Worm M., Arcangeli F. Efficacy and safety of methylprednisolone aceponate ointment 0,1% compared to tacrolimus 0,03% in children and adolescents with an acute flare of severe atopic dermatitis. Allergy. 2007;62(2):184-89.
  11. Torello A. Methylprednisolone aceponate for atopic dermatitis. Int. J. Dermatol. 2017;56(6):691-7.
  12. Регистр лекарственных средств России РЛС. https://www.rlsnet.ru
  13. Snyder R.D., Holt P.A., Maguire J.M., Trent J.O. Evidence for the contribution of non-covalent steroid interactions between DNA and topoisomerase in the genotoxicity of steroids. Drug Chem. Toxicol. 2015;38(2):212-9.
  14. Mehta A.B., Nadkarni N.J., Patil S.P., Godse K.V., Gautam M., Agarwal S. Topical corticosteroids in dermatology. Indi. J. Dermatol. Venereol. Leprol. 2016;82(4):371-78.
  15. Blume-Peytavi U., Wahn U. Optimizing the treatment of atopic dermatitis in children: a review of the benefit/risk ratio of methylprednisolone aceponate. J. Eur. Acad. Dermatol. Venerol. 2011;25:508-15.
  16. Machado S. Effective use of methylprednisolone aceponate 0,1% in a 9-month old infant with atopic eczema and sleep disturbance. J. Eur. Acad. Dermatol. Venerol. 2012;26(6):14-5.
  17. Torrelo A. Successful treatment of widespread eczema and sleep disruption in a 7-month old infant with methylprednisolone aceponate 0,1%. J. Eur. Acad. Dermatol. Venerol. 2012; 26(6):16-7.
  18. Metz M., Wahn U., Gieler U., Stock P., Schmitt J., Blume-Peytavi U. Chronic pruritus associated with dermatologic disease in infancy and childhood: update from an interdisciplinary group of dermatologists and pediatricians. Pediatr. Allergy lmmunol. 2013;24(6): 527-39.
  19. Garcia Ponte L., Ebert U. Frontiers of rapid itch relief: a review of methylprednisolone aceponate. J. Eur. Acad. Dermatol. Venereol. 2012; 26(6):9-13.
  20. Torrelo A. Methylprednisolone aceponate 0,1% in the treatment of pruritic lichenified eczema in a 3-year old child with chronic atopic dermatitis. J. Eur. Acad. Dermatol. Venerol. 2012; 26(6):16-7.
  21. Khamaganova l. Alleviation of a severe pruritic flare-up in a 13-year old child with chronic atopic dermatitis treated with methylprednisolone aceponate 0,1%. J. Eur. Acad. Dermatol. Venerol. 2012;26(6):20-1.
  22. Blume-Peytavi U., Metz M. Atopic dermatitis in children: management of pruritus. J. Eur. Acad. Dermatol. Venereol. 2012;26(6):2-8.
  23. Blume-Peytavi U., Wahn U. Optimizing the treatment of atopic dermatitis in children: a review of the benefit/risk ratio of methylprednisolone aceponate. J. Eur. Acad. Dermatol. Venereol. 2011;25(5):508-15.
  24. Peserico A., Städtler G., Sebastian M., Fernandez R.S., Vick K., Bieber T. Reduction of relapses of atopic dermatitis with methylprednisolone aceponate cream twice weekly in addition to maintenance treatment with emollient: a multicentre, randomized, double-blind, controlled study. Br. J. Dermatol. 2008;158(4):801-7.
  25. Szczepanowska J., Reich A., Szepietowski J.C. Emollients improve treatment results with topical corticosteroids in childhood atopic dermatitis: a randomized comparative study. Pediatr. Allergy Immunol. 2008;19(7):614-18.
  26. Mirshahpanah P., Döcke W.D., Merbold U., Asadullah K., Röse L., Schäcke H., Zollner T.M. Superior nuclear receptor selectivity and therapeutic index of methylprednisolone aceponate versus mometasone furoate. Exp. Dermatol. 2007;16(9):753-61.
  27. Prakash A., Benfield P. Topical mometasone. A review of its pharmacological properties and therapeutic use in the treatment of dermatological disorders. Drugs. 1998;55(1): 145-63.
  28. Balato N., Patruno C., Lembo G., Cuccurullo F.M., Ayala F. Contact sensitization to 6 alpha-methylprednisolone aceponate. Am. J. Contact. Dermat. 1997;8(1):24-5.

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