Cerebroprotective effects of fixed-dose combination of perindopril arginine/ indapamide


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Abstract

The article presents a clinical case illustrating the improvement of cognitive functions, an increase in cerebral blood flow, a decrease in the left ventricular myocardial mass index against the background of treatment of a patient with a previously untreated uncomplicated hypertension with a fixed combination of an angiotensin-converting enzyme inhibitor perindopril arginine and a diuretic indapamide. The possibilities of antihypertensive therapy, in particular, the combination of perindopril with indapamide in the correction of cognitive impairments in arterial hypertension and their pathogenetic mechanisms are discussed.

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About the authors

O. D Ostroumova

FSBEI HE MSMSU n.a. A.I. Evdokimov of RMH; FSAEI HE "First Moscow State Medical University n.a. I.M. Sechenov" of RMH

Email: ostroumova.olga@mail.ru
MD, Prof. at the Department of Faculty Therapy and Occupational Diseases; Prof. at the Department of Clinical Pharmacology and Propaedeutics of Internal Diseases Moscow

T. M Ostroumova

FSBEI HE MSMSU n.a. A.I. Evdokimov of RMH

Moscow

E. V Borisova

FSBEI HE MSMSU n.a. A.I. Evdokimov of RMH

Moscow

V. A Perepelov

FSBEI HE MSMSU n.a. A.I. Evdokimov of RMH

Moscow

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