Diabetic distal polyneuropathy: the principles of diagnostics and therapy


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Abstract

The article discusses the clinical manifestations of diabetic distal polyneuropathy (DPN), the diagnosis of this complication, and the principles of therapy. Particular attention is paid to the treatment of DPN with pregabalin (Lyrica). The review of studies on the efficacy and safety of the use of pregabalin in diabetic patients with DPN is presented. Indication for the prescription of pregabalin includes the presence of characteristic symptoms of DPN. The initial dosage is 150 mg/day with a dose titration every 7 days, if necessary. In general, the drug is well tolerated, the side effects are associated with the mechanism of its action, and are transient, as a rule. The drug can be taken for a long time without reducing its effectiveness.

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About the authors

E. Yu Komelyagina

SBHCI «Endocrinological Dispensary» of the Moscow Healthcare Department

Email: komelelena@yandex.ru

M. B Antsiferov

SBHCI «Endocrinological Dispensary» of the Moscow Healthcare Department

PhD, Head of the Department of Diabetic Foot

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