Effective possibilities of prevention of falls and fractures in patients with osteoporosis: focus on complex approach


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Abstract

According to the conclusion of the World Health Organization in 2016, the falls represent one of the global public health problems. In patients with osteoporosis, falls are the leading risk factor for severe fractures (femoral, spinal, pelvic, humerus). The risk factors for falls in the elderly patients are numerous and varied. Age-associated sarcopenia and vestibular disorders can be considered as the leading causes. Vitamin D - the basic agent for the prevention of falls in elderly patients. Due to a wide range of positive effects on bone strength, muscle tissue, balance and cognitive abilities, the use of vitamin D is an important preventive measure to reduce the incidence of falls and subsequent fractures in older people, since such treatment targets many risk factors for falls in elderly patients and strengthens the bone. Active vitamin D metabolites, in particular alfacalcidol, have a number of advantages over native forms in increasing muscle strength and reducing the risk of falls and fractures, but should be prescribed against a background of normal hydroxyvitamin D levels.

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About the authors

L. A Marchenkova

National Medical Research Center for Rehabilitation and Balneology

Email: MarchenkovaLA@rncmrik.com
PhD, Head of the Department of Rehabilitation of Patients with Somatic Diseases; Head of the Department of Active Longevity and Endocrinology

E. V Makarova

National Medical Research Center for Rehabilitation and Balneology

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