THE IMPORTANCE OF THE REFLUXATE NATURE FOR THE MANIFESTATION OF CLINICAL AND ENDOSCOPIC SYMPTOMS OF GASTROESOPHAGEAL REFLUX DISEASE
- Authors: Orziev Z.M1, Yuldasheva D.K.1
-
Affiliations:
- Bukhara State Medical Institute
- Issue: No 3S (2018)
- Pages: 17-21
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/296538
- DOI: https://doi.org/10.18565/pharmateca.2018.s3.17-20
- ID: 296538
Cite item
Open Access
Access granted
Abstract
Objective: to evaluate the possible association of the refluxate nature (RN) with the features of the leading clinical endoscopic signs of GERD. Methods. In order to support objectives, 74 patients with GERD were examined, 40 (54%) men and 34 (46%) women aged 18 to 57 years (mean age, 34±4.2 years). The diagnosis of GERD was verified based on the clinical and anamnestic, radiologic and endoscopic data using the GERD classification. Results. In cases of alkaline reflux, odynophagia, dysphagia and bitterness in the mouth were more pronounced; and with acid reflux, the significance of heartburn and eructation has increased significantly. Erosive esophagitis was more typical for acid reflux, and non-erosive esophagitis - for alkaline reflux. Conclusion. Based on the results of study, it can be concluded that RN makes a certain impact on the features of the manifestation of clinical and endoscopic signs of GERD.
Full Text
About the authors
Z. M Orziev
Bukhara State Medical Institute
Email: orzavman@mail.ru
MD, Prof. at the Department of Propaedeutics of Internal Diseases and Clinical Pharmacology
D. Kh Yuldasheva
Bukhara State Medical Institute
References
- Бабак О.Я., Фадеенко Г.Д. Гастроэзофагеальная рефлюксная болезнь. Киев, 2000. 175 c.
- Дельво М. Диагностика и лечение желудочно-пищеводного рефлюкс. Врач. 1994;5:12-4.
- Carrian M.Y. Cheung, Joseph J.Y. Sung, Justin C.Y. Wu., Vincent W.S. Wong. Различия клинических характеристик пациентов с неэрозивной рефлюксной болезнью и рефлюкс эзофагитом. Клиническая гастроэнтерология и гепатология. Русское издание. 2008;1(3):169-75.
- Мавлянов И.Р., Орзиев З.М., Маруфханов Х.М. О целесообразности создания новой клини ческой классссификации гастроэзофагеальной рефлюксной болезни. Медицинский журнал Узбекистана. 2009;5:98-101.
- Шарма Н., Агравал А., Фрееман Ж., и др. Анализ стойких симптомов гастроэзофагеальной рефлюксной болезни на фоне лечения ИПП с учетом данных рН - импедансометрии. Клиническая гастроэнтерология и гепатология. Русское издание. 2008;1(3):193-97.
- Рысс Е.С. Гастроэзофагеальная рефлюксная болезнь. Мир медицины. 1998;6(компьютерная версия).
- Шептулин А.А. Гастроэзофагеальная рефлюксная болезнь: спорные и нерешенные вопросы. Клиническая медицина. 2008;6:8-11.
- French-Belgian Consensus Conference on Adult Gastro-oesophageal Reflux Disease. Diagnosis and treatment report of a meeting held in Paris, France on 21-22 January 1999. The jury of the consensus conference. Eur. J. Gastroenterol. Hepatol. 2000;12:129-37.
- Lim L.G., Ho K.Y. Gastroesophageal reflux disease at the turn of millennium. World. J. Gastroenterol. 2003;9(10):2135-36.
- Rose S., Achkar E., Easley K. Gastroesophageal reflux disease. Dig. Dis. Sci. 1994;39:2063-68.
- Williams C.N. Gastroesophageal reflux disease. Can. J. Gastroenterol. 1998;40:132-38.
Supplementary files
