MYCOPLASMAL INFECTION - TOPICAL ISSUE IN PEDIATRICS
- Authors: Khadisova M.K1
-
Affiliations:
- Moscow Regional Scientific Research Clinical Institute n.a. M.F. Vladimirsky
- Issue: No 5S (2018)
- Pages: 90-95
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/296626
- ID: 296626
Cite item
Open Access
Access granted
Abstract
The article discusses the problem of mycoplasmal infection in pediatric practice. Mycoplasma pneumoniae is a fairly common agent of acute respiratory infections in children, which is the second most important etiologic factor in the development of community-acquired pneumonia in children older than 5 years. Mycoplasmal infection can occur in different clinical variants with varying degrees of severity, and the severity of the course and the spectrum of clinical manifestations, both respiratory and non-respiratory, are associated most with the virulence of the pathogen and the immune potential of the infected person. There is still a need to develop an readily accessible test for rapid diagnosis. Antibacterial therapy is recommended for the treatment of pneumonia and severe forms requiring hospitalization.
Full Text
About the authors
M. K Khadisova
Moscow Regional Scientific Research Clinical Institute n.a. M.F. Vladimirsky
Email: murzabekova.marina.1979@mail.ru
PhD, Researcher at the Department of Children’s Infectious Diseases
References
- Самсыгина Г.А. Микоплазмоз респираторного тракта у детей и подростков. Consiüium Medicum. Педиатрия (Приложение). 2011;4:67-70.
- Yamazaki T., Kenri T. Epidemiology of Mycoplasma pneumoniae Infections in Japan and Therapeutic Strategies for Macrolide-Resistant M. pneumoniae. Front. Microbiol. 2016;7:693. Doi: 10.3389/ fmicb.2016.00693.
- Sun H., Xue G., Yan C., et al. Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015. PLoS One. 2017;12(1):e0170253. doi: 10.1371/journal. pone.0170253.
- Liao J.Y., Zhang T. Distribution characteristics of Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila in hospitalized children with acute respiratory tract infection: an analysis of 13 198 cases. Zhongguo Dang Dai Er Ke Za Zhi. 2016;18(7):607-13.
- Хадисова М.К. Клинико-лабораторные особенности, вопросы терапии микоплазменной инфекции (Mycoplasma pneumoniae) у детей с острыми респираторными заболеваниями. Дисс. канд. мед. наук. 2013.
- Королева Е.Г., Осидак Л.В., Милькинт К.К. и др. Респираторная микоплазменная инфекция у детей с отягощенным преморбидным фоном. Детские инфекции. 2004:4:17-22.
- Narita M. Pathogenesis of extrapulmonary manifestations of Mycoplasma pneumoniae infection with special reference to pneumonia. J. Infect. Chemother. 2010;16:162-69. doi: 10.1007/s10156-010-0044-x.
- Харламова Ф.С., Шамшева О.В., Воробьева Д.А. и др. Микоплазменная инфекция у детей: современная диагностика и терапия. Детские инфекции. 2016;15(3):50-7. Doi: 10.1234/ XXXX-XXXX-2016-3-50-57.
- Izumikawa K. Clinical Features of Severe or Fatal Mycoplasma pneumoniae Pneumonia. Front. Microbiol. 2016;7:800. Doi: 10.3389/ fmicb.2016.00800.
- Saraya T., Nakata K., Nakagaki K., et al. Identification of a mechanism for lung inflammation caused by Mycoplasma pneumoniae using a novel mouse model. Results Immunol. 2011;1(1):76-87. doi: 10.1016/j.rinim.2011.11.001.
- Chaudhry R., Ghosh A., Chandolia A. Pathogenesis of Mycoplasma pneumoniae: An update. Ind. J. Med. Microbiol. 2016;34(1):7-16. doi: 10.4103/0255-0857.174112. Review.
- Techasaensiri C., Tagliabue C., Cagle M., et al. Variation in colonization, ADP-ribosylating and vacuolating cytotoxin, and pulmonary disease severity among mycoplasma pneumoniae strains. Am. J. Respir. Crit. Care Med. 2010;182(6):797-804. doi: 10.1164/rccm.201001-00800C.
- Jiang W., Yan Y., Ji W., et al. Clinical significance of different bacterial load of Mycoplasma pneumoniae in patients with Mycoplasma pneumoniae pneumonia. Braz. J. Infect. Dis. 2014;18:124-28. doi: 10.1016/j.bjid.2013.06.004.
- Внебольничная пневмония у детей. Клинические рекомендации. Российское респираторное общество. Межрегиональное педиатрическое респираторное общество. Федерация педиатров стран СНГ. Московское общество детских врачей. М., 2015. 64 с.
- Савенкова М.С., Савенков М.П., Самитова Э.Р. и др. Микоплазменная инфекция: клинические формы, особенности течения, ошибки диагностики. Вопросы современной педиатрии. 2013;12(6):108-14.
- Bajantri B., Venkatram S., Diaz-Fuentes G. Mycoplasma pneumoniae: A Potentially Severe Infection. J. Clin. Med. Res. 2018;10(7):535-44. doi: 10.14740/jocmr3421w.
- Nilsson A.C., Bjorkman P., Persson K. Polymerase chain reaction is superior to serology for the diagnosis of acute Mycoplasma pneumoniae infection and reveals a high rate of persistent infection. BMC. Microbiol. 2008;8:93.
- Lee W.J., Huang E.Y., Tsai C.M., et al. Role of Serum Mycoplasma pneumoniae IgA, IgM, and IgG in the Diagnosis of Mycoplasma pneumoniae-Related Pneumonia in School-Age Children and Adolescents. Clin. Vaccine Immunol. 2017;24(1):e00471-16. doi: 10.1128/CVI.00471-16.
- Spuesens E.B., Fraaij P.L., Visser E.G., et al. Carriage of Mycoplasma pneumoniae in the upper respiratory tract of symptomatic and asymptomatic children: an observational study. PLoS Med. 2013;10(5):e1001444. doi: 10.1371/journal. pmed.1001444.
- Pereyre S., Goret J., Bébéar C. Mycoplasma pneumoniae: Current Knowledge on Macrolide Resistance and Treatment. Front Microbiol. 2016;7:974. doi: 10.3389/fmicb. 2016.00974.
Supplementary files
