Postradiation bowel diseases - how to help the patient?
- Authors: Osipenko M.F.1, Bikbulatova E.A1, Loginova A.B1
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Affiliations:
- Novosibirsk State Medical University
- Issue: Vol 27, No 2 (2020)
- Pages: 80-83
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/312521
- DOI: https://doi.org/10.18565/pharmateca.2020.2.80-83
- ID: 312521
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Abstract
Post-radiation bowel diseases are a common problem in patients after radiation therapy for cancer. The small intestine, rectum and sigmoid colon are the most commonly affected. Lesions can be both acute and chronic, and occur in a fairly long-term period. There are not only morphological, but also functional changes that are clinically manifested by diarrhea, pain, bacterial overgrowth, bleeding, malabsorption, strictures, and intestinal fistulas. Severe bowel damage can lead to permanent disability. The treatment is mainly symptomatic, but in case of complications can be surgical. A number of studies have shown the protective and therapeutic effects of some drugs, but the evidence base is still insufficient.
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About the authors
Marina F. Osipenko
Novosibirsk State Medical University
Email: ngma@bk.ru
Dr. Sci. (Med.), Professor, Head of the Department of Propaedeutics of Internal Diseases, Faculty of Medicine, Head of the Department for Organization and Coordination of Dissertational and Scientific Councils Novosibirsk, Russia
E. A Bikbulatova
Novosibirsk State Medical UniversityDepartment of Propaedeutics of Internal Diseases Novosibirsk, Russia
A. B Loginova
Novosibirsk State Medical UniversityDepartment of Propaedeutics of Internal Diseases Novosibirsk, Russia
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