Clinical case of the use of a combination of paclitaxel and carboplatin in the treatment of metastatic urachus tumor
- Authors: Kunafina R.I.1, Sakaeva D.D1, Urmantsev M.F1, Suleymanova R.R1
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Affiliations:
- Bashkir State Medical University, BSMU Clinic
- Issue: Vol 27, No 11 (2020)
- Pages: 73-76
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/312887
- DOI: https://doi.org/10.18565/pharmateca.2020.11.73-76
- ID: 312887
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Abstract
Background. The detection rate of urachus cancer is 0.35-0.7% of all cases of oncological pathology of the bladder and only 0.01% of all malignant tumors. Due to the low prevalence of urachus tumors to date, there are no uniform recommendations for palliative chemotherapy for this nosology. Description of the clinical case. The article describes a case of treatment of a rare urachus tumor with a combination of paclitaxel and carboplatin with a response to therapy. Conclusion. Palliative chemotherapy with paclitaxel+carboplatin made it possible to stabilize the disease for 4 months and preserve the patient’s satisfactory quality of life.
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About the authors
Regina I. Kunafina
Bashkir State Medical University, BSMU Clinic
Email: kunafinareg2017@yandex.ru
Oncologist, Head of the Department of Chemotherapy 2, Shafieva str., Ufa 450059, Russian Federation
D. D Sakaeva
Bashkir State Medical University, BSMU ClinicUfa, Russia
M. F Urmantsev
Bashkir State Medical University, BSMU ClinicUfa, Russia
R. R Suleymanova
Bashkir State Medical University, BSMU ClinicUfa, Russia
References
- Reuter V The Urothelial tract: Renal pelvis, ureter, urinary bladder and urethra. Philadelphia: Lippincott Williams and Wilkins. 2004. Р 2062-63.
- Kumar N, Khosla D., Kumar R., et al. Urachal carcinoma: Clinicopathological features, treatment and outcome. J Cancer Res Ther. doi: 10.4103/0973-1482.137955.
- Нюшко КМ, Алексеев Б.Я., Каприн А.Д. Рак урахуса. Онкология. Журнал им. П.А.Герцена. 2015;4(3):43-7.
- Henly D.R., Farrow G.M., Zincke H. Urachal cancer: role of conservative surgery. Urol. 1993;42:635-39. doi: 10.1016/0090-4295(93)90526-g.
- Siefker-Radtke A.O., Gee J., Shen Y, et al. Multimodality management of urachal carcinoma: the M.D. Anderson Cancer Center experience. J Urol. 2003;169:1295-98. doi: 10.1097/01. ju.0000054646.49381.01.
- Sheldon C.A., Clayman R.V, Gonzalez R, et al. Malignant urachal lesions. J Urol. 1984;131(1):1-8 doi: 10.1016/s0022-5347(17)50167-6.
- Paul A.B., Hunt C.R., Harney J.M., et al. Stage 0 mucinous adenocarcinoma in situ of the urachus. J Clin Pathol. 1998;51:483-84. Doi: 10.1136/ jcp.51.6.483.
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