A clinical case of thrombotic complications in a patient with hereditary thrombophilia and pulmonary arteriovenous malformation
- Authors: Ivanova M.I1, Ikonnikov P.P2, Maznev D.S2, Kozak A.A1, Lisukova P.V1
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Affiliations:
- North-Western State Medical University n.a. I.I. Mechnikov
- City Multidisciplinary Hospital № 2, St. Petersburg
- Issue: Vol 27, No 13 (2020)
- Pages: 147-151
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/312995
- DOI: https://doi.org/10.18565/pharmateca.2020.13.147-151
- ID: 312995
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Abstract
Background. Currently, strokes, especially in young patients, are a significant medical and social problem. Differential diagnosis of the causes of stroke development in young patients is important from the point of view of the prevention of recurrent events. Description of the clinical case. This article examines a clinical case of multiple thrombotic events in a young woman with congenital thrombophilia (heterozygous FII [prothrombin] gene mutation) in combination with pulmonary arteriovenous malformation. Conclusion. A comprehensive examination and determining the mechanisms of thrombosis development made it possible to determine the individual risk factors, treatment tactics for the patient, which dramatically reduced the risk of recurrent cerebrovascular accidents. The identification of hereditary disorders determined not only the possibility of secondary prevention of the disease in the patient, but also the dynamic follow-up and primary prevention for her children.
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About the authors
M. I Ivanova
North-Western State Medical University n.a. I.I. Mechnikov
Email: ivanovamaiiaig@mail.iu
P. P Ikonnikov
City Multidisciplinary Hospital № 2, St. Petersburg
D. S Maznev
City Multidisciplinary Hospital № 2, St. Petersburg
A. A Kozak
North-Western State Medical University n.a. I.I. Mechnikov
P. V Lisukova
North-Western State Medical University n.a. I.I. Mechnikov
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