Hypoglycemic syndrome: justification for standardized diagnostic approach

Background. Doctors of different specialties can face hypoglycemic syndrome due to the nonspecific symptoms of this condition. In order to avoid diagnostic errors and prevent complications of hypoglycemia, as well as the appointment of unreasonable examinations for patients with unproven organic hyperinsulinism, it is necessary to follow a clear diagnostic algorithm. Description of a series of clinical cases. This article presents a description of the clinical cases of two patients with suspected hypoglycemic syndrome observed in the Clinic of Rostov State Medical University in 2020-2021. Both patients had identical complaints and medical history. However, endogenous hyperinsulinism was confirmed in the first patient; and in the second one, hypoglycemic syndrome was excluded. Therefore, the tactics of management and treatment of these patients differed. Conclusion. In most cases, hypoglycemia is the result of an overdose of insulin or sulfonylureas in diabetic patients. Patients without diabetes require differential diagnosis with a wide range of diseases, including rare and life-threatening ones.

hypoglycemia, glucose, insulin, hypoglycemic syndrome, proinsulinoma, clinical case