Hypertriglyceridemia-induced pancreatitis: a clinical case


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Abstract

Background. Pancreatitis, which develops against the background of hypertriglyceridemia, occurs quite rarely, but is characterized by a severe course. Metabolic and nutritional factors are involved in the development of the disease. The recurrent course of hypertriglyceridemia-induced pancreatitis (HTIP) leads to the formation of fibrosis of the pancreatic parenchyma and a decrease in its exo- and endocrine functions. Description of the clinical case. A clinical case of a recurrent course of pancreatitis against the background of hypertriglyceridemia, combined with the development of comorbid pathology, in a 30-year-old man is presented. The difficulty in diagnosing HTIP in this case was associated with the combination of moderate hypercholesterolemia with high triglyceride levels and unchanged blood and urine amylase levels during the exacerbation period. Conclusion. This clinical case demonstrates the difficulties in diagnosing HTIP due to the features of the clinical course of the disease, due to the combined influence of nutritional factors and dyslipidemia. Achieving positive clinical and laboratory dynamics, regression of exacerbation episodes require complex etiopathogenetic therapy, as well as adherence to dietary recommendations.

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About the authors

M. V Malykh

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department

K. A Nikolskaya

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department

L. V Vinokurova

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department

K. A Lesko

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department

N. V Boyko

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department

N. A Savenkova

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department

A. V Andrianov

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department; A.I. Yevdokimov Moscow State University of Medicine and Dentistry; Tver State Medical University

D. S Bordin

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department

Elena A. Dubtsova

A.S. Loginov Moscow Clinical Scientific and Practical Center of the Moscow Healthcare Department

Dr. Sci. (Med.), Head of the Department of Pathology of the Pancreas and Biliary Tracts

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