Laser therapy and phototherapy for rosacea

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Rosacea is a non-communicable dermatological disease of middle age that requires long-term and often life-long treatment. The debut of the disease begins with minor clinical manifestations, such as centrofacial transient erythema or conjunctivitis, which is not considered by patients as a need to see a doctor. Early therapy prevents chronicity of the process and the development of severe forms, such as papulopustular rosacea, ophthalmic rosacea and phimosis. One of the methods of rosacea therapy is physiotherapy, including laser therapy, cryotherapy, darsonvalization, electrophoresis, electrocoagulation, pulse therapy, inductothermy, phototherapy of vascular pathology, etc. This review presents the main mechanisms of the action of laser light on human skin and systematizes data on its use in various forms of rosacea.

Full Text

Restricted Access

About the authors

Yuliya I. Matushevskaya

Lyubertsy Dermatovenerologic Dispensary

Email: yuliya-matushevskaya@yandex.ru
Cand. Sci. (Med.), Chief Physician Lyubertsy, Moscow Region, Russia

References

  1. Yazici A.C., Tamer L., Ikizoglu G., et al. GSTM1 and GSTT1 null genotypes as possible heritable factors of rosacea. Photodermatol Photoimmunol Photomed. 2006;22:208-10. doi: 10.1111/j.1600-0781.2006.00220.x.
  2. Srivastava D.S.L., Jain V.K., Verma P, Yadav J.P Polymorphism of glutathione S-transferase M1 and T1 genes and susceptibility to psoriasis disease: A study from North India. Indian J. Dermatol Venereol Leprol. 2018;84(1):39-44. doi: 10.4103/ijdvl.IJDVL_1128_16.
  3. Guo H, Huang Y., Wu J., et al. Correlation analysis of the HLA-DPB1*05:01 and BTNL2 genes within the histocompatibility complex region with a clinical phenotype of psoriasis vulgaris in the Chinese Han population. J Gene Med. 2017;19(9-10). doi: 10.1002/jgm.2961.
  4. Chang A.L.S., Raber I., Xu J., et al. Assessment of the genetic basis of rosacea by genome-wide association study. J Invest Dermatol. 2015;135(6):1548-55. Doi: 10.1038/ jid.2015.53.
  5. Rhodes DA, Reith W., Trowsdale J. Regulation of Immunity by Butyrophilins. Ann. Rev. Immunol. 2016;34:151-72. doi: 10.1146/annurev-immunol-041015-055435.
  6. Chaperon M., Pacheco Y., Maucort-Boulch D., et al. BTNL2 gene polymorphism and sarcoid uveitis. Br J Ophthalmol. 2019. pii: bjophthalmol-2018-312949. Doi: 10.1136/ bjophthalmol-2018-312949.
  7. Tolentino Y.F., Elia P.P., Foga a H.S., et al.Common NOD2/CARD15 and TLR4 Polymorphisms Are Associated with Crohn's Disease Phenotypes in Southeastern Brazilians. Dig Dis Sci. 2016;61(9):2636-47. doi: 10.1007/s10620-016-4172-8.
  8. Marrani E, Cimaz R., Lucherini O.M., et al. The common nodx/card variant pzoqs in patients with non-infectious uveitis: a cohort study. Pediatr Rheumatol Online J. 2015;13(1):38. doi: 10.1186/sl2969-015-0037-5.
  9. Angeletti S., Galluzzo S., Santini D., et al. NOD2/CARD15 polymorphisms impair innate immunity and increase susceptibility to gastric cancer in an Italian population. Hum. Immunol. 2009;70(9):729-32. Doi: 10.1016/j. humimm.2009.04.026.
  10. Salzer S., Kresse S., Hirai Y., et al. Cathelicidin peptide LL-37 increases UVB-triggered inflammasome activation: possible implications for rosacea. J Dermatol Sci. 2014;76(3):173- 79. doi: 10.1016/j.jdermsci.2014.09.002.
  11. Yamasaki K., Gallo R.L. Rosacea as a disease of cathelicidins and skin innate immunity. J Investig Dermatol Symp. Proc. 2011;15(1):12-5. doi: 10.1038/jidsymp.2011.4.
  12. Gokiinar N.B., Karabulut A.A., Onaran Z., et al. Elevated Tear Human Neutrophil Peptides 1-3, Human Beta Defensin-2 Levels and Conjunctival Cathelicidin LL-37 Gene Expression in Ocular Rosacea. Ocul Immunol Inflamm. 2019;27(7):1174-83. doi: 10.1080/09273948.2018.1504971.
  13. Yamasaki K., Kanada K., Macleod D.T., et al. TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. J Invest Dermatol. 2011;131(3):688-97. Doi: 10.1038/ jid.2010.351.
  14. Meyer-Hoffert U., Schroder J.M. Epidermal proteases in the pathogenesis of rosacea. J Investig Dermatol Symp Proc. 2011;15(1):16-23. doi: 10.1038/jidsymp.2011.2.
  15. Muto Y., Wang Z., Vanderberghe M., et al. Mast cells are key mediators of cathelicidin-initiated skin inflammation in rosacea. J Invest Dermatol. 2014;134(11):2728-36. Doi: 10.1038/ jid.2014.222.
  16. Zaidi A.K., Spaunhurst K., Sprockett D., et al. Characterization of the facial microbiome in twins discordant for rosacea. Exp Dermatol. 2018;27(3):295-8. doi: 10.1111/exd.13491.
  17. Clanner-Engelshofen B.M., Bernhard D., Dargatz S., et al. S2k guideline: Rosacea. J Dtsch Dermatol Ges. 2022;20(8):1147-65. doi: 10.1111/ddg.14849.
  18. Searle T., Ali F.R., CarolidesS., Al-Niaimi F Rosacea and Diet: What is New in 2021? J. Aesthet. Dermatol. 2021;14(12):49-54.
  19. Silverman H.A., Chen A., Kravatz N.L., et al. Involvement of Neural Transient Receptor Potential Channels in Peripheral Inflammation. Front Immunol. 2020;11:590261. Doi: 10.3389/ fimmu.2020.590261.
  20. Ziolkowski N., KittoS.C.,Jeong D., et al. Psychosocial and quality of life impact of scars in the surgical, traumatic and burn populations: a scoping review protocol. BMJ. Open. 2019;9(6):e021289. doi: 10.1136/bmjopen-2017-021289.
  21. Anderson R.R., Parrish J.A. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Sci. 1983;220(4596):524-27. Doi: 10.1126/ science.6836297.
  22. Alam M., Voravutinon N., Warycha M., et al.Comparative effectiveness of nonpurpuragenic 595-nm pulsed dye laser and microsecond 1064nm neodymium:yttrium-aluminum-garnet laser for treatment of diffuse facial erythema: A doubleblind randomized controlled trial. J Am Acad Dermatol. 2013;69(3):438-43. Doi: 10.1016/j. jaad.2013.04.015.
  23. Campos M.A., Sousa A.C., Varela P, et al.Comparative effectiveness of purpuragenic 595 nm pulsed dye laser versus sequential emission of 595 nm pulsed dye laser and 1,064 nm Nd:YAG laser: a double-blind randomized controlled study. Acta Dermatovenerol Alp Pannonica Adriat. 2019;28(1):1-5.
  24. Kwon WJ, Park B.W., Cho E.B., et al.Comparison of efficacy between long-pulsed Nd:YAG laser and pulsed dye laser to treat rosacea-associated nasal telangiectasia. J Cosmet Laser Ther. 2018;20(5):260-64. doi: 10.1080/14 7641 72.201 7.1418510.
  25. Salem S.A., Abdel Fattah N.S., Tantawy S.M., et al. Neodymium-yttrium aluminum garnet laser versus pulsed dye laser in erythemato-telangiectatic rosacea: comparison of clinical efficacy and effect on cutaneous substance (P) expression. J Cosmet Dermatol. 2013;12(3):187-94. Doi: 10.1111/ jocd.12048.
  26. Handler M.Z., Bloom B.S., Goldberg D.J. IPL vs PDL in treatment of facial erythema: A split-face study. J. Cosmet. Dermatol. 2017;16(4):450-53. doi: 10.1111/jocd.12365.
  27. Kim B.Y, Moon H.R., Ryu H.J.Comparative efficacy of short-pulsed intense pulsed light and pulsed dye laser to treat rosacea. J Cosmet Laser Ther. 2019;21(5):291-96. doi: 10.1080/14764172.2018.1528371.
  28. Neuhaus I.M., Zane L.T, Tope W.D.Comparative efficacy of nonpurpuragenic pulsed dye laser and intense pulsed light for erythematotelangiectatic rosacea. Dermatol Surg. 2009;35(6):920-28. doi: 10.1111/j.1524-4725.2 009.01156.x.
  29. Nymann P., Hedelund L., Haedersdal M. Long-pulsed dye laser vs.intense pulsed light for the treatment of facial telangiectasias: a randomized controlled trial. J Eur Acad Dermatol. Venereol. 2010;24(2):143-46. doi: 10.1111/j.1468-3083.2009.03357.x.
  30. Tanghetti E.A. Split-face randomized treatment of facial telangiectasia comparing pulsed dye laser and an intense pulsed light handpiece. Lasers Surg Med. 2012;44(2):97-102. Doi: 10.1002/ lsm.21151.
  31. West T.B., Alster T.S.Comparison of the long-pulse dye (590-595 nm) and KTP (532 nm) lasers in the treatment of facial and leg telangiectasias. Dermatol Surg. 1998;24(2):221-26. doi: 10.1111/j.1524-4725.1998.tb04140.x.
  32. Kim S.J., Lee Y., Seo Y.J., et al.Comparative Efficacy of Radiofrequency and Pulsed Dye Laser in the Treatment of Rosacea. Dermatol Surg. 2017;43(2):204-9. Doi: 10.1097/ DSS.0000000000000968.
  33. Paasch U., Zidane M., Baron J.M., et al. S2k guideline: Laser therapy of the skin. J Dtsch Dermatol Ges. 2022;20(9):1248-67. doi: 10.1111/ddg.14879.
  34. Husein-ElAhmed H., Steinhoff M. Light-based therapies in the management of rosacea: a systematic review with meta-analysis.Int J Dermatol. 2022;61(2):216-25. Doi: 10.1111/ ijd.15680.
  35. Luo Y., Luan X.L., Zhang J.H., et al. Improved telangiectasia and reduced recurrence rate of rosacea after treatment with 540 nm-wavelength intense pulsed light: A prospective randomized controlled trial with a 2-year follow-up. Exp Ther Med. 2020;19(6):3543-50. Doi: 10.3892/ etm.2020.8617.
  36. Liu J., Liu J., Ren Y., et al.Comparative efficacy of intense pulsed light for different erythema associated with rosacea. J Cosmet Laser Ther. 2014;16(6):324-27. Doi: 10.3 1 09/14764 1 72.2014.95 72 18.
  37. Шаршунова А.А., Круглова Л.С., Котенко К.В., Софинская Г.В. Этиопатогенез и возможности лазеротерапии эритематозно-телеангиэктатического подтипа розацеа. Физиотерапия, бальнеология и реабилитация. 2017;16(6):284-90.
  38. Toyos R., Desai N.R., Toyos M., Dell S.J.Intense pulsed light improves signs and symptoms of dry eye disease due to meibomian gland dysfunction: A randomized controlled study. PLoS One. 2022;17(6):e0270268. doi: 10.1371/journal. pone.0270268.
  39. Amaral M.T.S.S.D., Haddad A., Nahas F.X., et al. Impact of Fractional Ablative Carbon Dioxide Laser on the Treatment of Rhinophyma. Aesthet Surg. J. 2019;39(4):NP68-75. Doi: 10.1093/ asj/sjy234.
  40. Kassirer S.S., Gotkin R.H., Sarnoff D.S. Treatment of Rhinophyma With Fractional CO2 Laser Resurfacing in a Woman of Color: Case Report and Review of the Literature. J Drugs Dermatol. 2021;20(7):772-75. doi: 10.36849/JDD. C702.
  41. Bassi A., Campolmi P., Dindelli M., et al. Laser surgery in rhinophyma. J. Ital. Dermatol. Venereol. 2016;151(1):9-16.
  42. Badawi A., Osman M., Kassab A. Novel Management of Rhinophyma by Patterned Ablative 2940nm Erbium:YAG Laser. Clin Cosmet Investig Dermatol. 2020;13:949-55. doi: 10.2147/CCID.S286847.
  43. Li A., Fang R., Mao X., Sun Q. Photodynamic therapy in the treatment of rosacea: A systematic review. Photodiagnos Photodyn Ther. 2022;38:102875. doi: 10.1016/j.pdpdt.2022.102875.
  44. Friedmann D.P, Goldman M.P, Fabi S.G., Guiha I. Multiple sequential light and laser sources to activate aminolevulinic acid for rosacea. J Cosmet Dermatol. 2016;15(4):407-12. Doi: 10.1111/ jocd.12231.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies