The effectiveness of intimate biorevitalization in the treatment of symptoms of vulvovaginal atrophy

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Resumo

Background. The problems of women’s reproductive aging and the need to maintain and improve the quality of life and health of women during the period of age-related changes are an urgent task of modern medicine, especially in the light of existing demographic trends. Genitourinary menopausal syndrome (GUMS) is a symptom complex that occurs in women against the background of a deficiency of estrogens and other sex steroids, including physiological and anatomical changes in the vagina, urethra, bladder, vulva and perineum.

Objective. Evaluation of the effectiveness of vulva biorevitalization with preparations based on hyaluronic acid (HA) in combination with hardware methods for the relief of local symptoms of GUMS and lichen sclerosus (LS).

Methods. The study included 40 patients: 20 with GUMS (group 1) and 20 with LS (group 2). The follow-up period was up to 6 months. Patients aged 24–65 years were included, the median age of patients in both groups was 42 years. Injections with MesoHydral or Hydro Line Extra (in both groups) or Nucleospire DNA-RNA 2% (only in the LS group) were administered. All patients tolerated the procedures well, there were no side effects, and the patients were satisfied with the treatment.

Conclusion. Thus, preparations of this type can be recommended not only for practical use, but also for further, possibly more detailed and broad study of the spectrum of their capabilities.

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Sobre autores

A. Saidova

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Email: i_apolikhina@oparina4.ru
Rússia, Moscow

A. Dudkina

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Email: i_apolikhina@oparina4.ru
Rússia, Moscow

T. Teterina

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Email: i_apolikhina@oparina4.ru
Rússia, Moscow

Inna Apolikhina

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Sechenov University

Autor responsável pela correspondência
Email: i_apolikhina@oparina4.ru
ORCID ID: 0000-0002-4581-6295

Dr. Sci. (Med.), Professor, Head of the Department of Aesthetic Gynecology and Rehabilitation; Professor at the Department of Obstetrics, Gynecology, Perinatology and Reproductology, Institute of Postgraduate Education

Rússia, Moscow; Moscow

Bibliografia

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2. Fig.1. Intradermal administration of HA preparations (biorevitalization)

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3. Fig.2. IVZ in HUMS and SL groups before treatment

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4. Fig.3. IVZ in HUMS and SL groups after treatment

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5. Fig.4. Appearance of the vulva before and after treatment. Patient K., 24 years old. Diagnosis: SL of the vulva

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6. Fig.5. Appearance of the vulva before and after treatment. Patient P., 53 years old. Diagnosis: GUMS

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7. Fig.6. Appearance of the vulva before and after treatment. Patient E., 30 years old. Diagnosis: SL of the vulva

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8. Fig.7. Appearance of the vulva before and after treatment. Patient R., 59 years old. Diagnosis: GUMS

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9. Fig.8. Appearance of the vulva before and after treatment. Patient Z., 43 years old. Diagnosis: SL of the vulva

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10. Fig.9. Appearance of the vulva before and after treatment. Patient E., 55 years old. Diagnosis: GUMS

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