Pyogenic granuloma of the nail bed, clinical cases and literature review

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Abstract

The article analyzes current information about pyogenic granuloma (PG), currently referred to as benign vascular tumors. The features of the clinical course of the disease are considered in detail, the factors that most often provoke the development of PG are described, a detailed description of the dermatoscopic picture is presented, with such signs as a reddish homogeneous area, white collar, white rail structures, ulceration and vascular structures. Special attention is paid to the differential diagnosis of PG with non-pigmented melanoma of the skin, Spitz nevus, lymphangiomas, angiokeratomas, bacillary angiomatosis, Kaposi’s sarcoma and basal cell skin cancer. The authors present their own clinical observations of PG in the nail bed, illustrating the possibility of self-regression, as well as the possibility of using a topical β-blocker for the treatment of PG in children.

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About the authors

Ekaterina K. Murakhovskaya

Russian Medical Academy of Continuous Professional Education

Author for correspondence.
Email: murakhovskayaek@mail.ru
ORCID iD: 0000-0002-3126-3618
SPIN-code: 2862-2889

Cand. Sci. (Med.), Teaching Assistant at the Department of Dermatovenereology and Cosmetology

Russian Federation, Moscow

Tatiana A. Sysoeva

Russian Medical Academy of Continuous Professional Education

Email: murakhovskayaek@mail.ru
ORCID iD: 0000-0002-3426-4106
SPIN-code: 1919-6461
Russian Federation, Moscow

Inna B. Mertsalova

Russian Medical Academy of Continuous Professional Education

Email: murakhovskayaek@mail.ru
ORCID iD: 0009-0000-3992-1032
SPIN-code: 5206-9083
Russian Federation, Moscow

M. R. Aleksandrova

Russian Medical Academy of Continuous Professional Education

Email: murakhovskayaek@mail.ru
Russian Federation, Moscow

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Supplementary files

Supplementary Files
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2. Fig.1. PG in a 58-year-old patient in the chin area, which appeared 1.5 months ago at the site of a cut while shaving

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3. Fig.2. Dermatoscopic picture of PG and its schematic representation: a) a reddish homogeneous area, represented by a structureless zone of a whitish-reddish color; b) a white “collar” in the form of an arched whitish structure surrounding the formation on the periphery; c) white rail-type structures in the form of white stripes crossing the lesion; d) vascular structures represented by polymorphic vessels

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4. Fig.3. Patient S., 35 years old; a) PG of the third finger of the right hand, clinical picture upon presentation; b) clinical picture 3 weeks after the initial treatment: regression of PG; c) destruction of the proximal edge of the NP; d) clinical picture 3 months after the initial treatment: regrowth of a healthy NP; e) clinical picture after 1 year: complete recovery of NP

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5. Fig.4. Patient M., 8 years old: a) PG of the first toe of the right foot, clinical picture upon presentation; b) clinical picture after 2 months: complete recovery of NP

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