Anogenital forms of lichen planus: current concepts and a clinical case

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Dermatosis localized in the anogenital regionis an urgent problem of modern medicine, requiring the involvement of physicians of various specialties. Difficulties in the differential diagnosis of dermatosis in anogenital area determine the formation of severe clinical forms and torpidity to the treatment. It is important to note that in case of late diagnosis, there is a possibility of serious complications, especially in the absence of adequate treatment of dermatoses in anogenital area. The problem of differential diagnosis lies in the similar clinical picture of most skin diseases, and the effectiveness of treatment depends on the accuracy of the diagnosis. The article presents current data on epidemiology, etiopathogenesis, provoking factors, clinical features of various forms of lichen planus (LP) in anogenital area. The relationship of LP with pathological conditions such as autoimmune diseases, malignant neoplasms, viral hepatitis C, presence of dyslipidemia, hypothyroidism and diabetes in a patient is discussed. Particular attention is paid to the hypertrophic variant of LP in anogenital area, which has the most difficult clinical picture to diagnose and is the least described in the scientific literature. The authors present a complex interdisciplinary clinical case of LP in anogenital area. Dynamic monitoring, the involvement of related specialists and the use of various diagnostic methods, such as laboratory tests, dermatoscopy, histological examination, transdermal imaging methods (ultrasound, MRI), is often required. Ccombined work of a dermatovenereologist, proctologist, obstetrician-gynecologist, urologist, oncologist, pathomorphologist and the surgeon provides faster and more accurate diagnosis of diseases, which in turn allows to choose timely and adequate treatment tactics. The presented clinical case will help practitioners to better navigate the issues of diagnosing skin diseases in anogenital area.

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作者简介

Aleksey Khryanin

Novosibirsk State Medical University; Association of Obstetricians-Gynecologists and Dermatovenereologists

编辑信件的主要联系方式.
Email: khryanin@mail.ru
ORCID iD: 0000-0001-9248-8303

Dr. Sci. (Med.), Professor, Department of Dermatovenereology and Cosmetology; President

俄罗斯联邦, Novosibirsk; Novosibirsk

A. Nadeev

Novosibirsk State Medical University

Email: khryanin@mail.ru
ORCID iD: 0000-0003-0400-1011
俄罗斯联邦, Novosibirsk

A. Sokolovskaya

Novosibirsk State Medical University

Email: khryanin@mail.ru
ORCID iD: 0000-0002-3131-7874
俄罗斯联邦, Novosibirsk

O. Sotsenko

“MDT” Medical Center

Email: khryanin@mail.ru
ORCID iD: 0009-0007-1897-6860
俄罗斯联邦, Belgorod

参考

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补充文件

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1. JATS XML
2. Fig.1. External genitalia of the patient O. 1A - Enlargement, swelling and hyperemia of the labia majora; 1B - View of the perianal area, fibrous changes and swelling of external hemorrhoids

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3. Fig.2. Histological examination of skin biopsy. Hematoxylin and eosin staining

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