Pathology of the skin and mucous membranes in children with HIV infection
- Authors: Pozdnyakova O.N.1, Bychkov S.G.2, Nemchaninova O.B.1, Reshetnikova T.B.1
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Affiliations:
- Novosibirsk State Medical University
- Novosibirsk Regional Clinical Dermatovenerological Dispensary
- Issue: Vol 30, No 13 (2023)
- Pages: 14-18
- Section: Reviews
- URL: https://journals.eco-vector.com/2073-4034/article/view/625917
- DOI: https://doi.org/10.18565/pharmateca.2023.13.14-18
- ID: 625917
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Abstract
The article is devoted to a review of the literature on modern international views on the pathology of the skin and mucous membranes in children with human immunodeficiency virus (HIV) infection. The issues of the prevalence of dermatoses among the peiatric population with HIV infection are emphasized, skin diseases that are most common in this population are presented. The problems of their classification depending on the etiology, as well as the degree of immunosuppression are determine. The features of the clinical course of diseases of the skin and mucous membranes in HIV-infected children are reported. Current trends in the structure of dermatological pathology in pediatric patients taking antiretroviral therapy, its side effects that have a negative effect on the skin and mucous membranes, as well as the most common skin manifestations of the inflammatory syndrome of immune system restoration in the form of viral diseases are discussed.
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About the authors
O. N. Pozdnyakova
Novosibirsk State Medical University
Email: pharmateca@yandex.ru
ORCID iD: 0000-0003-1389-1001
Russian Federation, Novosibirsk
S. G. Bychkov
Novosibirsk Regional Clinical Dermatovenerological Dispensary
Author for correspondence.
Email: Stasbychkov9409@mail.ru
ORCID iD: 0000-0002-9135-5274
Dermatovenereologist
Russian Federation, Novosibirsk Regional Clinical Dermatovenerological DispensaryO. B. Nemchaninova
Novosibirsk State Medical University
Email: pharmateca@yandex.ru
ORCID iD: 0000-0002-5961-6980
Russian Federation, Novosibirsk
T. B. Reshetnikova
Novosibirsk State Medical University
Email: pharmateca@yandex.ru
ORCID iD: 0000-0002-6156-0875
Russian Federation, Novosibirsk
References
- World Heaths Organization. HIV/AIDS. URL: https://www.who.int/ru/news-room/fact-sheets/detail/hiv-aids
- Joint United Nations Programme on HIV/AIDS. Fact Sheet – Global HIV Statistics. URL: https://www.unaids.org/en/resources/fact-sheet
- Клинические рекомендации «ВИЧ-инфекция у детей». Национальная ассоциация специалистов по профилактике, диагностике и лечению ВИЧ-инфекции. 2020. [Clinical guidelines «HIV infection in children.» National Association of Specialists in the Prevention, Diagnostics and Treatment of HIV Infection. 2020. (In Russ.)].
- Беляков Н.А., Рассохин В.В., Трофимова Т.Н. и др. Коморбидные и тяжелые формы ВИЧ-инфекции в России. ВИЧ-инфекция и иммуносупрессии. 2016;8(3):9–25. [Belyakov N.A., Rassokhin V.V., Trofimova T.N., et al. Comorbid and severe forms of HIV infection in Russia. VICh-infektsiya i immunosupressii. 2016;8(3):9–25. (In Russ.)].
- Frigati L.J., Ameyan W., Cotton M.F., et al. Chronic comorbidities in children and adolescents with perinatally acquired HIV infection in sub-Saharan Africa in the era of antiretroviral therapy. Lancet Child Adolesc Health. 2020;4(9):688–98. doi: 10.1016/S2352-4642(20)30037-7.
- Mukwasi-Kahari C., Rehman A.M., Ó Breasail M., et al. Impaired Bone Architecture in Peripubertal Children With HIV, Despite Treatment With Antiretroviral Therapy: A Cross-Sectional Study From Zimbabwe. J. Bone Miner. Res. 2023;38(2):248–60. doi: 10.1002/jbmr.4752.
- Idris N.S., Uiterwaal C.S.P.M., Burgner D.P., et al. Effects of HIV Infection on Pulmonary Artery Pressure in Children. Glob. Heart. 2019;14(4):367–72. doi: 10.1016/j.gheart.2019.08.006.
- Duko B., Gebrie M., Deribe B., et al. Patterns of common skin infections among children living with HIV/AIDS in Hawassa City, Ethiopia: a cross sectional study. BMC. Res Notes. 2018;11(1):881. doi: 10.1186/s13104-018-3991-4.
- Endayehu Y., Mekasha A., Daba F. The pattern of mucocutaneous disorders in HIV infected children attending care and treatment in Tikur Anbesa specialized hospital, Addis Ababa, Ethiopia. BMC. Dermatol. 2013;13:12. doi: 10.1186/1471-5945-13-12.
- Dias E.D., Cunha Mda G., Talhari S. The profile of the dermatoses in children with the HIV virus at the Fundacao de Medicina Tropical do Amazonas. An Bras Dermatol. 2012;87(3):396–402. doi: 10.1590/s0365-05962012000300007.
- Mankahla A., Mosam A. Common skin conditions in children with HIV/AIDS. Am J Clin Dermatol. 2012;13(3):153–66. doi: 10.2165/11593900-000000000-00000.
- Ward H.A., Russo G.G., Shrum J. Cutaneous manifestations of antiretroviral therapy. J Am Acad Dermatol. 2002;46:284–93.
- Oyedeji O.A., Oninla S.O., Bolaji O.B., et al. Muco-Cutaneous Infections in HIV Infected Children at a Nigerian Tertiary Hospital. West Afr J Med. 2022;39(4):362–68.
- Pirofski L. Fungal infections in children with human immunodeficiency virus infection. Semin Pediatr Infect Dis. 2001;12(4):288–95.
- Mofensen L.M., Oleske J., Serchuck L., et al. Treating opportunistic infections among HIV-exposed and infected children: recommendations from CDC, the National Institutes of Health, and Infectious Diseases Society of America. Clin Infect Dis. 2005;40(Suppl. 1):S1–84.
- Hogan M.T. Cutaneous infestations associated with HIV/AIDS. Dermatol Clin. 2006;24:473–95.
- Stefanaki C., Stratigos A.J., Stratigos J.D. Skin manifestations of HIV-1 in children. Clin Dermatol. 2002;20:74–86.
- Lowe S., Ferrand R.A., Morris-Jones R., et al. Skin disease among human immunodeficiency virus-infected adolescents in Zimbabwe: a strong indicator of underlying HIV infection. Pediatr Infect Dis J. 2010;29(4): 346–51.
- Castelnuovo B., Byakwaga H., Menten J., et al. Can response of a pruritic popular eruption to antiretroviral therapy be used as a clinical parameter to monitor virologic outcome? AIDS. 2008;22:269–73.
- HIV Classification: CDC and WHO Staging Systems AIDS Education and Training Centers National Coordinating Resource Center (AETC NCRC). URL: http://aidsetc.org/guide/hiv-classification-cdc-and-who-staging-systems.
- Olomukoro C.N., Dlova N.C., Sibanda W., et al. Mucocutaneous diseases in the combined antiretroviral therapy era: prevalence and spectrum in HIV seropositive children and adolescents in Durban, South Africa. Int J Dermatol. 2022;61(3):259–65. doi: 10.1111/ijd.15735.
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