Phototechnologies in the treatment of melasma

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Abstract

Background. The mechanism by which IPL systems are able to improve pigmentation is unclear, but the formation of intraepidermal microcrusts with their subsequent exfoliation has been proposed.

Objective. Evaluation of the effectiveness of melasma monotherapy with intense pulsed light (IPL).

Methods. The study involved 15 female patients, aged 27–42 years, mean age 34.5±3.2 years. Mexametry and the MASI index were used as control methods.

Results. Both according to mexametry data and the MASI scale, the use of IPL monotherapy in patients with melasma with epidermal pigment has shown pronounced clinical effectiveness, which allows to recommend its use in practical healthcare.

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About the authors

A. T. Semizidis

Lancet Clinic

Email: pharmateca@yandex.ru
ORCID iD: 0009-0007-5413-0125
Russian Federation, Gelendzhik

N. E. Manturova

Pirogov Russian National Research Medical University

Author for correspondence.
Email: plasticafedra@gmail.com
ORCID iD: 0000-0003-4281-1947

Dr. Sci. (Med.), Chief External Expert in Plastic Surgery of the Ministry of Health of the Russian Federation, Head of the Department of Plastic and Reconstructive Surgery, Cosmetology and Cell Technologies

Russian Federation, Moscow

References

  1. Потекаев Н.Н., Круглова Л.С. Лазер в дерматологии и косметологии. М., 2018. 280 с. [Potekaev N.N., Kruglova L.S. Laser in dermatology and cosmetology. M., 2018. 280 p. (In Russ.)].
  2. Mehrabi J.N., Bar-Ilan E., Wasim S., et al. A review of combined treatments for melasma involving energy-based devices and proposed pathogenesis-oriented combinations. J Cosmet Dermatol. 2022;21(2):461–72. doi: 10.1111/jocd.14110.
  3. Trivedi M.K., Yang F.C., Cho B.K. A review of laser and light therapy in melasma. Int J Womens Dermatol. 2017;3(1):11–20. doi: 10.1016/j.ijwd.2017.01.004.
  4. Yamashita T., Negishi K., Hariya T., et al. Intense pulsed light therapy for superficial pigmented lesions evaluated by reflectance-mode confocal microscopy and optical coherence tomography. J Invest Dermatol. 2006;126(10):2281–86. doi: 10.1038/sj.jid.5700414.
  5. Потекаев Н.Н., Круглова Л.С. Гиперпигментация: причины возникновения и методы коррекции. Клиническая дерматология и венерология. 2012;10(6):65–70. [Potekaev N.N., Kruglova L.S. Hyperpigmentation: causes and methods of correction. Clinical dermatology and venereology. 2012;10(6):65–70. (In Russ.)].
  6. Gonzalez-Ojeda A., et al. Treatment of melasma with platelet-rich plasma: A self-controlled clinical trial. Dermatol Ther. 2022;35(9):e15703. doi: 10.1111/dth.15703.

Supplementary files

Supplementary Files
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1. JATS XML
2. Рис. 1. Эффективность терапии мелазмы с помощью IPL через 1 и 6 месяцев после терапии, по данным мексаметрии, %

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3. Рис. 2. Эффективность терапии мелазмы с помощью IPL до и через 1 месяц после терапии, по данным шкалы MAS|

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4. Рис. 3. Эффективность терапии мелазмы с помощью IPL до и через 6 месяцев после терапии, по данным шкалы MAS|

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