A clinical case of celiac disease and ulcerative colitis in a child

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Abstract

Inflammatory bowel disease (IBD) and celiac disease are autoimmune diseases. For the manifestation of these diseases, an external trigger activating the pathological reaction of the immune system is necessary. Such clinical manifestations as diarrhea or constipation, delayed physical development and recurrent abdominal pain syndrome can occur both in IBD and celiac disease. Patients with celiac disease, especially those who do not show positive dynamics on a gluten-free diet, are examined for the possible presence of IBD, since these two conditions can coexist. At the same time, if pathogenetic therapy for IBD is insufficiently effective (dyspeptic disorders and protein-energy malnutrition persist), celiac disease must also be excluded. This article describes a clinical case of celiac disease in an adolescent with a previously verified diagnosis of ulcerative colitis.

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About the authors

Aelita A. Kamalova

Kazan State Medical University; Children’s Republican Clinical Hospital

Email: aelitakamalova@gmail.com

Dr. Sci. (Med.), Professor of the Department of Hospital Pediatrics

Russian Federation, Kazan; Kazan

Galina A. Garina

Kazan State Medical University

Author for correspondence.
Email: galinagalina.gala@yandex.ru
ORCID iD: 0000-0002-4333-8779
SPIN-code: 9227-1828

Postgraduate Student, Department of Hospital Pediatrics

Russian Federation, Kazan

Gulnara M. Yakupova

Children’s Republican Clinical Hospital

Email: gulnara66doc@gmail.com

Head of the Gastroenterology Department

Russian Federation, Ufa

Anastasia G. Kuznetsova

Children’s Republican Clinical Hospital

Email: stsi2008@rambler.ru

Pathologist

Russian Federation, Ufa

Railya A. Nizamova

Children’s Republican Clinical Hospital

Email: nizamova.railya@gmail.com

Head of the Diagnostic Department, Pediatrician, Gastroenterologist

Russian Federation, Ufa

Nailya R. Mingacheva

Children’s Republican Clinical Hospital

Email: Nelya-min@yandex.ru

Resident Physician, Department of Hospital Pediatrics

Russian Federation, Ufa

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Supplementary files

Supplementary Files
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1. JATS XML
2. Rice. 1. Histological changes in celiac disease

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3. Fig. 2. Comparison of BMI/age Z-score in the first hospitalization (-4.01) and the second (-3.47)

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4. Fig. 3. Comparison of height/age Z-score in the first hospitalization (-1.27) and the second (-0.29)

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