Goflikicept: a new promising drug for the treatment of recurrent pericarditis

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Abstract

Recurrent idiopathic pericarditis is an autoimmune inflammatory disease of the pericardium characterized by repeated episodes of inflammation after 4–6 weeks of remission. This article examines the historical development and current understanding of the pathogenesis of recurrent pericarditis as an interleukin-1 (IL-1)-dependent autoinflammatory disease. It describes the efficacy of targeted therapy compared to standard treatments and the advantages of goflikicept, the first and only Russian drug, compared to other IL-1 antagonists. The paper also examines the results of a study of its safety profile and efficacy during long-term therapy.

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A. V. Vydashenko

Order of the Red Banner of Labor Institute named after S.I. Georgievsky

Email: denis.elagin@vk.com
ORCID iD: 0000-0002-0351-8185
Russian Federation, Simferopol

D. V. Elagin

Order of the Red Banner of Labor Institute named after S.I. Georgievsky

Author for correspondence.
Email: denis.elagin@vk.com
ORCID iD: 0009-0006-6252-0636
SPIN-code: 2546-8230

Student

Russian Federation, Simferopol

M. I. Sheremet

Order of the Red Banner of Labor Institute named after S.I. Georgievsky

Email: denis.elagin@vk.com
ORCID iD: 0009-0003-2011-0805
Russian Federation, Simferopol

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