Znachenie antioksidantnoy terapii v lechenii diabeticheskoy polinevropatii

详细

A peripheral nerve lesion, a diabetic polyneuropathy (DPN), is typical late complication of type 1 and 2 diabetes mellitus (DM). The article presents the data on the pathogenetic mechanisms of the nervous system involvement in DM, classification of lesions, and principles of treatment of DPN. Special attention is paid to the use of a-lipoic acid as compound that plays a key role in the antioxidant defense system. The success of the prevention and treatment of DPN involves early detection of this complication and a comprehensive approach, including the normalization of glycemia and the use of drugs affecting the pathogenetic mechanisms of DPN.