CAN SYSTEMIC SKLERODERMIA BE A REASON FOR DEVELOPMENT OF THE STROKE? ANALYSIS OF CLINICAL OBSERVATION

Background. Systemic scleroderma (SS) is one of the rarest forms of collagenosis, and as many researchers note, primary damage to the central nervous system is much less likely with this disease. In the literature, cases of development of stroke and transient ischemic attacks in patients with SS are usually represented by single observations. However, with the use of modern methods of neuroimaging, the frequency of detection of individuals who have had a stroke against the background of the SS may be significantly higher. Description of the clinical case. The clinical observation of 66-year-old SS patient with ischemic stroke developed against the background of the rapidly progressing course of SS is presented. This case reflects the complexity of diagnosis and treatment in the pre-stroke period with the combination of SS and peripheral vascular disease, as well as difficulties and interpretation of the causes of stroke in such patients. Conclusion. After discussing the presented observation at the pathoanatomical conference, the causal relationship between the SS and the developed multifocal cerebral infarction was confirmed, the pathogenetic variant of ischemic stroke was reviewed: the atherothrombotic subtype was replaced by the «other established etiology» according to the TOAST classification.

acute cerebrovascular disorders, ischemic stroke, systemic scleroderma, peripheral vascular disease, differential diagnosis