The course and outcome of pregnancies in women with an episode of missed miscarriage after a comprehensive rehabilitation

Background. In order to reduce reproductive losses, the creation and introduction of new organizational and medical technologies to restore women’s health after a missed miscarriage (MM) is an urgent task. Objective. Improvement of the outcomes of subsequent pregnancies in women with history of MM. Methods. A retrospective, open, comparative case-control study included 233 women. They were divided into 2 groups depending on the presence (n=117) or absence (n=116) of rehabilitation after emptying the uterus due to MM. Comparative analysis of the course and outcome of subsequent pregnancy for 1 year was performed. Comprehensive rehabilitation included antibacterial therapy, hormonal therapy and physiotherapy. Results. After rehabilitation, the onset of pregnancy after treatment in group I was earlier than in group II (1-4 versus 4-6 months, respectively; p<0.05). Placental insufficiency and polyhydramnios were statistically less frequent (1.2 vs 9.6 %; p=0.33 and 12.6 vs 28.9%; p=0.015, respectively). 82.8% of pregnancies in group I and 54.2% in group II (p<0.001) ended with delivery in time. It was revealed that with the use of vacuum aspiration and the drug method for emptying the uterus due to MM followed by rehabilitation, the frequency of delivere in time was statistically significantly higher compared to uterine curettage (78.5 vs 60%; p=0.04 and 100 vs 63.6%; p=0.05, respectively). Conclusion. Comprehensive rehabilitation for women after the MM episode made it possible to improve the course and outcomes of a subsequent pregnancy

missed miscarriage, rehabilitation, reproductive function, pregnancy outcome