Retrospective analysis of a clinical case of sepsis in a patient with liver cirrhosis

Background. In recent decades, the growth of septic conditions has been associated with an increase in life expectancy, the proportion of patients with immune deficiency conditions, the number of invasive interventions, and the development of resistance of key microorganisms to antibacterial drugs. Despite decades of intensive scientific research on septic syndrome, early diagnosis of sepsis in practice is associated with difficulties due to the extreme heterogeneity of the population of such patients, the variability of clinical manifestations and the lack of a «gold» diagnostic standard. Description of the clinical case. The article presents a clinical case of a fatal course of sepsis in a patient with cirrhotic stage of hepatitis after closed reduction of prosthetic hip joint dislocation. In a retrospective analysis of this clinical case, the reasons for the late diagnosis of a septic condition were analyzed. Conclusion. For early detection of a septic process, especially in the presence of severe underlying pathology, it is necessary to conduct a detailed dynamic assessment of the condition using the APACHE III, SOFA (qSOFA) scales and determine the procalcitonin level.

sepsis, mortality, liver cirrhosis, clinical case, SOFA scale, systemic inflammatory response