VOPROSY LEChENIYa RAKA POLOSTI RTA


Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Acesso é pago ou somente para assinantes

Resumo

The article is dedicated to the choice of treatment for squamous cell carcinoma of the oral mucosa. The early stages of the disease are quite successfully treated using only surgery or radiation treatment, whereas locally advanced tumors require an integrated approach. According to the literature data, modern surgery, radiotherapy and chemotherapy provide great potentials for the successful treatment of patients. The choice of the sequence of stages of the combined treatment is a difficult question. Numerous publications on the subject are inconclusive, and have not justified the use of radiation therapy in the first stage of disease, although it is conventional in Russia. A review of the introduction of targeted therapies in the schemes for the treatment of the both locally advanced and recurrent processes is presented.

Texto integral

Acesso é fechado

Sobre autores

I. Romanov

L. Yakovleva

Bibliografia

  1. Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2007 г. // Вестник РОНЦ им. Н.Н. Блохина РАМН 2009. Т. 20. № 3. Прил. 1. 158 с.
  2. Гарбузов М.И. Лучевая терапия первичных злокачественных опухолей слизистой оболочки полости рта. Дисс. докт. мед. наук. М., 1982. 47 с.
  3. Mendenhall W.M., Van Cise W.S., Bova F.J., Million R.R. Analysis of time-dose factors in squamous cell carcinoma of the oral tongue and floor of mouth treated with radiation therapy alone. Int J Radiat Oncol Biol Phys 1981;7:1005-11.
  4. O'Brien C.J., Lahr C.J., Soong S.J., et al. Surgical treatment of early-stage carcinoma of the oral tongue - wound adjuvant treatment be beneficial? Head NeckSurg 1986;8:401-8.
  5. Spiro R.H., Spiro J.D., Strong E.W. Surgical approach to squamous carcinoma confined to the tongue and the floor of the mouth. Head Neck Surg 1986;9:27-31.
  6. Pernot M., Hoffstetter S., Peiffert D., et al. Epidermoid carcinomas of the floor of mouth treated by exclusive irradiation: statistical study of a series of 207 cases. Radiother Oncol 1995;35:177-85.
  7. Fein D.A., Mendenhall W.M., Parsons J.T., et al. Carcinoma of the oral tongue: a comparison of results and complications of treatment with radiotherapy and/or surgery. Head Neck multimodality treatment concepts] Mund Kiefer Gesichtschir 2006;10(1):30-6.
  8. Bernier J., Domenge C., Ozsahin M., et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004;350(19):1945-52.
  9. Lorch J.H., Posner M.R., et al. Long-term results from TAX324: A phase III trial of sequential therapy comparing TPF to PF in locally advanced (LA) squamous cell cancer of the head and neck (HNC), J Clin Oncol 2010 ASCO Annual Meeting Proceedings, 28(15S), Abstr. 5512.
  10. Pignon J.P., le Matre A., Maillard E., Bourhis J. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiother Oncol 2009;92(1):4-14.
  11. Lefebvre J., Pointreau Y., Rolland.F, et al: Results of the randomized phase II TREMPLIN study. 2011 ASCO Annual Meeting. Abstract 5501, Presented June 6, 2011.
  12. Zelefsky M.J., Harrison L.B., Fass D.E., et al. Postoperative radiation therapy for squamous cell carcinomas of the oral cavity and oropharynx: impact of therapy on patients with positive surgical margins. Int J Radiat Oncol Biol Phys 1993;25:17-21.
  13. Bernier J., Cooper J.S. Chemoradiation after surgery for high-risk head and neck cancer patients: how strong is the evidence? Oncologist 1994;16:358-65.
  14. Gregoire V., Lefebvre J-L., Licitra L., Felip E. Клинические рекомендации ESMO по диагностике, лечению и наблюдению при плоскоклеточном раке головы и шеи. В сб.: Минимальные клинические рекомендации европейского общества медицинской онкологии (ESMO) / Под редакцией русского перевода С.А. Тюляндина, Д.А. Носова, Н.И. Переводчиковой. М., 2010. C. 279-87.
  15. Современные методы диагностики и лечения рака слизистой оболочки полости рта / Материалы научной конференции Самара, 16-17 апреля 2010 г. М., 2011. 47 с.
  16. Klug C., Wutzl A., Kermer C., et al. Preoperative radiochemotherapy and radical resection for stages II-IV oral and oropharyngeal cancer: outcome of 222 patients. Int J Oral Maxillofac Surg 2005;34(2):143-48.
  17. Klug C., Berzaczy D., Voracek M., Millesi W. Preoperative chemoradiotherapy in the management of oral cancer: a review. J Craniomaxillofac Surg 2008;36(2):75-8.
  18. Eckardt A., Wegener G., Karstens J.H. Praoperative Radio-Chemo-Therapie fortgeschrittener, resektabler Mundhöhlenkarzinome mit Cisplatin vs. Paclitaxel/Carboplatin Analyse zweier multimodaler Therapiekonzepte [Preoperative radiochemotherapy of advanced resectable cancer of the oral cavity with cisplatin vs paclitaxel/carboplatin. Analysis of two2005;10:215-24.
  19. Mira E., Benazzo M., Rossi V., Zanoletti E. Efficacy of selective lymph node dissection in clinically negative neck. Otolaryngol Head Neck surg 2002;127:279-83.
  20. Buckley J.G., Feber T. Surgical treatment of cervical node metastases from squamous cell carcinoma of the upper aerodigestive tract: evaluation of the evidence from modifications of neck dissection. Head Neck 2001;3:907-15.
  21. Pitman K.T., Johnson J.T., Myers E.N. Effectiveness of selective neck dissection for management of the clinically negative neck. Arch Otolaryngol Head Neck Surg 1997;123:917-22.
  22. Vandenbrouck C., Sancho-Garnier H., Chassagne D., et al. Elective versus therapeutic radical neck dissection in epidermoid carcinoma of the oral cavity: results of a randomized clinical trial. Cancer 1980;46(2):386-90.
  23. Fakih A.R., Rao R.S., Borges A.M., et al. Elective versus therapeutic neck dissection in early carcinoma of the oral tongue. Am J Surg 1989;158(4):309-13.
  24. Piedbois P., Mazeron J.J., Haddad E., et al. Stage I-II squamous cell carcinoma of the oral cavity treated by iridium-192: is elective neck dissection indicated? Radiother Oncol 1991;21(2):100-6.
  25. Haddadin K.J., Soutar D.S., Oliver R.J., et al. Improved survival for patients with clinically T1/T2, N0 tongue tumors undergoing a prophylactic neck dissection. Head Neck 1999;21(6):517-25.
  26. Hosal A.S., Carrau R.L., Johnson J.T., Myers E.N. Selective neck dissection in the management of the clinically node-negative neck. Laryngoscope 2000;110:2037-40.
  27. Shah J.P., Candela F.C., Poddar A.K. The patterns of cervical lymph node metastases from squamous carcinoma of the oral cavity. Cancer 1990;66(1):109-13.
  28. Teichgraeber J.F., Clairmont A.A. The incidence of occult metastases for cancer of the oral tongue and floor of the mouth: treatment rationale. Head Neck 1984;7:15-21.
  29. van den Brekel M.W., van Waal I., Meijer C.J., Freeman J.L., Castelijns J.A., Snow G.B. The incidence of micrometastases in neck dissection specimens obtained from elective neck dissections. Laryngoscope 1996;106:987-91.
  30. Ogura J.H., Biller H.F., Wette R. Elective neck dissection for pharyngeal and laryngeal cancers. Ann Otol 1971;80:646-51.
  31. Lee J.G., Krause C.J. Radical neck dissection: elective, therapeutic, and secondary. Arch Otolaryngol 1975;101:656-59.
  32. McGuirt W.F. Jr., Johnson J.T., Myers E.N., et al. Floor of mouth carcinoma in management of the clinically negative neck. Arch Otolaryngol Head Neck Surg 1995;121:278-82.
  33. Yuen A.P.W., Wei W.I., Wong Y.M., et al. Elective neck dissection versus observation in the treatment of early oral tongue carcinoma. Head Neck 1997;19:583-88.
  34. Schantz S.P., Harrison L.B., Forastiere A. Tumors of the nasal cavity and paranasal sinuses, nasopharynx, oral cavity, and oropharynx. In: Cancer: Principles and Practice of Oncology. DeVita V.T., Hellman S.A., Rosenberg S.A. (Eds). Lippincott Williams & Wilkins, PA, USA 2001:797-860.
  35. Vermorken J.B., Mesia R., Rivera F., et al. Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer. N Engl J Med 2008;359:1116-27.

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML
Baixar

Declaração de direitos autorais © Bionika Media, 2013

Este site utiliza cookies

Ao continuar usando nosso site, você concorda com o procedimento de cookies que mantêm o site funcionando normalmente.

Informação sobre cookies