OPYT PRIMENENIYa NOVOY LEKARSTVENNOY FORMY PREPARATA TEMOZOLOMID: RASShIRYaYa VOZMOZhNOSTI LEChENIYa
- Autores: Naskhletashvili D.R1, Sharabura T.M1
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Afiliações:
- Edição: Nº 8 (2013)
- Páginas: 66-70
- Seção: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/281223
- ID: 281223
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Resumo
Temozolomide is the most effective drug for the treatment of malignant gliomas. All patients included in the study and treated with temozolomide in both dosage forms have reported better tolerance of intravenous infusion in comparison with oral capsules. Advantages of intravenous infusion of the temozolomida best implemented in patients with impaired swallowing, as well as children. Limitations of use of lyophilisate include necessity for admission of patient in a medical facility. However, the low toxicity of intravenous infusion of temozolomide allowed to recommend administration of this drug in a day hospital or in outpatient settings. Thus, the presence of two formulations enhances the use of temozolomide in patients with malignant gliomas, allows to provide treatment with low toxicity and ensure the highest quality of life during treatment.
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Bibliografia
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