Implantiruemye morfinovye pompy v terapii khronicheskogo bolevogo sindroma u onkologicheskikh bol'nykh. Pervyy klinicheskiy opyt

The article describes the first experience of testing methodology of chronic intrathecal therapy with implantable programmable pumps in Russia. The study was aimed to development of method for the therapy of severe chronic pain syndrome (CPS) for the improvement of quality of life of patients receiving high doses of opioid analgesics by prolonged intrathecal administration of micro-doses of morphine using programmable implantable pump. The study included 10 patients, 9 of them - with HBS of cancer genesis, and 1 patient - with non-tumor pathology. The first step included morphine test; positive test was the indication for the pump implantation. The pain intensity was assessed by standard rating scales. All patients have reported better pain relief, no systemic opioid-related side effects and improvement of quality of life after the selection of the individual mode of morphine administration using pump.

neuromodulation, chronic pain syndrome, programmable morphine pump, intrathecal administration