VOZMOZhNOSTI PRIMENENIYa MAGNITNOREZONANSNOY TOMOGRAFII V UTOChNENNOY DIAGNOSTIKE GEPATOTsELLYuLYaRNOGO RAKA


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The study including 25 patients with hepatocellular carcinoma has evaluated the potentials for the accurate differential diagnosis of hepatocellular carcinoma (HCC) using the hepato-specific contrast agent, a gadoxetic acid (Primovist), and diffusion-weighted magnetic resonance imaging (DWI). It was found that the combination of a number of MRI signs - diffuse heterogeneous "amplification" of focus in the arterial phase, rapid "washout" of contrast agent in the venous phase (with persistent heterogeneity of the internal structure of the focus), hyperintensity on DWI with isointensity on ICD-cards and hypointensity of focus in hepatospecific phase - allows to reliable identify such detectable focal lesion as HCC.

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参考

  1. Seale M.K., Catalano O.A., Saini S., Hahn P.F., Sahani D.V. Hepatobiliary-specific MR Contrast Agents: Role in Imaging the Liver and Biliary Tree. Radiographics 2009; 29: 1725-48.
  2. Lee M.H., Kim S.H., Park M.J., Park C.K., Rhim H. Gadoxetic Acid-Enhanced Hepatobiliary Phase MRI and High-b-Value Diffusion-Weighted Imaging to Distinguish Well-Differentiated Hepatocellular Carcinomas From Benign Nodules in Patients With Chronic Liver Disease. AJR November 2011 197: W868-W875; doi: 10.2214/AJR. 10.6237.
  3. Lee J.M., Trevisani F., Vilgrain V., Wald C. Imaging Diagnosis and Staging of Hepatocellular Carcinoma. Liver Transpl 2011; 17(10, Suppl 2): S34-S43.
  4. Nasu K., Kuroki Y., Tsukamoto T., et al. Diffusion-Weighted Imaging of Surgically Resected Hepatocellular Carcinoma: Imaging Characteristics and Relationship Among Signal Intensity, Apparent Diffusion Coefficient, and Histopathologic Grade. AJR 2009; 193: 438-44.

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