RECOMMENDATIONS FOR USE OF THE RUSSIAN MODEL FRAX® FOR DETERMINING 10-YEAR PROBABILITY OF OSTEOPOROTIC FRACTURES


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详细

The article is devoted to justification of creation, calculation methodology and interpretation of results of FRAX® algorithm to determine the 10-year probability of osteoporotic fractures. Age-related therapeutic intervention thresholds for the Russian population are presented, and coefficients of recalculation for patients receiving glucocorticoid treatment, depending on their dose, are given.

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作者简介

N. Toroptsova

Email: torop@irramn.ru
FSBIS «Scientific Research Institute of Rheumatology n.a. V.A. Nasonova» MD, Head of Laboratory of Osteoporosis Moscow

I. Baranova

SBEIHPE «Russian National Scientific Medical University n.a. N.I. Pirogov» of RMH Moscow

O. Lesnyak

SBEI HPE «Northwestern State Medical University n.a. I.I. Mechnikov» of RMH, SBEI HPE «Ural State Medical University» of RMH St.-Petersburg Yekaterinburg

参考

  1. Weinwright S.A., Marshall L.M., Ensrud K.E., Cauley J.A., Black D.M., Hillier T.A., Hochberg M.C., Vogt M.T., Orwoll E.S. Hip fracture in women without osteoporosis. J. Clin. Endocrinol. Metab. 2005;90(5):2787-93.
  2. Sanders K.M., Nicholson G.C., Watts J.J., Pasco J.A., Henry M.J., Kotowicz M.A., Seeman E. Half the burden of fragility fractures in the community occur in women without osteoporosis. When is fracture prevention cost-effective? Bone. 2006;38(5):694-700.
  3. Kanis J.A., Oden A., Johnell O., et al. The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. Osteoporos Int. 2007;18:1033-46.
  4. Баранова И.А., Торопцова Н.В., Лесняк О.М. Основные положения клинических рекомендаций «Диагностика, профилактика и лечение глюкокортикоидного остеопороза у мужчин и женщин 18 лет и старше». Остеопороз и остеопатии. 201;3:34-7.
  5. Kanis J.A., Johansson H., Oden A., McCloskey E. Guidance for the adjustment of FRAX according to the dose of glucocorticoids. Osteoporos Int. 2011;22:809-16.
  6. Leslie W.D., Lix L.M., Johansson H., Oden A., McCloskey E., Kanis J.A. Spine-hip discordance and fracture risk assessment: a physician-friendly FRAX enhancement. Osteoporos Int. 2011;22:839-47.

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