FOREARM BONE MINERAL DENSITY AS A PREDICTOR OF AXIAL OSTEOPOROSIS IN POSTMENOPAUSAL WOMEN WITH PRIOR LOW-ENERGY BONE FRACTURES


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅或者付费存取

详细

The study was aimed to the evaluation of the possibility of using peripheral X-ray densitometry of distal forearm to predict the axial osteoporosis in postmenopausal women with prior low-energy fractures of major osteoporotic sites. The study included 134 postmenopausal women (mean age - 64.5±8.7 years) with prior low-energy fractures of the 5 locations (thigh, forearm, humeral neck, spine and ankle), who underwent densitometry of the lumbar spine and proximal femur and densitometry of distal forearm. Correlation coefficients between bone mineral density of distal forearm and proximal femur in general, femoral neck and lumbar spine were 0.58, 0.62 and 0.47, respectively. Based on ROC-curves and determination of sensitivity and specificity for different cut points, optimal values of T-score of the distal forearm were selected, allowing to predict osteoporosis in the lumbar spine, femoral neck and proximal femur as a whole with a sensitivity of 72-75 % and a specificity of 71-76%. It was concluded that peripheral densitometry of distal forearm can be used in postmenopausal women with prior low-energy fractures to predict the axial osteoporosis if central dual-energy X-ray absorptiometry is unavailable.

全文:

受限制的访问

作者简介

O. Dobrovolskaya

FSBIS «SRIR n.a. V.A. Nasonova» Moscow

N. Demin

FSBIS «SRIR n.a. V.A. Nasonova» Moscow

N. Toroptsova

Email: torop@irramn.ru
FSBIS «SRIR n.a. V.A. Nasonova» MD, Head of Laboratory of Osteoporosis Moscow

参考

  1. Simonelli C., Chen Y., Morancey J., Lewis A.F., Abbott T.A. Evaluation and management of osteoporosis following hospitalization for low-impact fracture. J. Gen. Intern. Med. 2003;18(1):17-22.
  2. Schurink M., Hegeman J.H., Kreeftenberg H.G., Ten Duis H.J. Follow-up for osteoporosis in older patients three years after a fracture. Neth. J. Med. 2007;65(2):71-4.
  3. Estrand J., Thorngren K-G. One fracture is enough! Experience with a prospective and consecutive osteoporosis screening program with 239 fracture patients. Acta Orthopaedica. 2006;77(1):3-8.
  4. Follin S.L., Black J.N., McDermott M.T. Lack of diagnosis and treatment of osteoporosis in men and women after hip fracture. Pharmacotherapy. 2003;23(2):190-98.
  5. Balasubramanian A., Tosi L.L., Lane J.M., Dirschl D.R., Ho P.R., O'Malley C.D. Declining rates of osteoporosis management following fragility fractures in the U.S., 2000 through 2009. J. Bone Joint Surg. Am. 2014;96(7):е52.
  6. Евстигнеева Л.П., Кузнецова Е.В., Низамутдинова Р.М., Лаврентьев А.С. Выявляемость и лечение остеопороза у пациентов старших возрастных групп с переломом дистального отдела предплечья. Уральский медицинский журнал. 2010;7:91-6.
  7. Elliot-Gibson V., Bogoch E.R., Jamal S.A., Beaton D.E. Practice patterns in the diagnosis and treatment of osteoporosis after a fragility fracture: a systematic review. Osteoporos. Int. 2004;15(10):767-78.
  8. Лесняк О.М. Аудит состояния проблемы остеопороза в Российской Федерации. Профилактическая медицина. 2011;2:7-10.
  9. Kanis J.A., Johnell O. Requirements for DXA for the management of osteoporosis in Europe. Osteoporos. Int. 2005;16:3:229-38.
  10. Boonen S., Cheng X., Nicholson P.H., Verbeke G., Broos P., Dequeker J. The accuracy of peripheral skeletal assessment at the radius in estimating femoral bone density as measured by dualenergy X-ray absorptiometry: a comparative study of single-photon absorptiometry and computed tomography. J. Intern. Med. 1997;242(4):323-28.
  11. Damilakis J., Papadokostakis G., Perisinakis K., Hadjipavlou A., Gourtsoyiannis N. Can radial bone mineral density and quantitative ultrasound measurements reduce the number of women who need axial density skeletal assessment? Osteoporos. Int. 2003;14(8):688-93.
  12. Dhainaut A., Rohde G.E., Syversen U., Johnsen V., Haugeberg G. The ability of hand digital X-ray radiogrammetry to identify middle-aged and elderly women with reduced bone density, as assessed by femoral neck dual-energy X-ray absorptiometry. J. Clin. Densitom. 2010;13(4):418-25.
  13. http://www.iscd.org/official-positions/2015-iscd-official-positions-adult
  14. Youden W.J. Index for rating diagnostic tests. Cancer. 1950;3:32-5.
  15. Pouillès J.M., Tremollières F.A., Martinez S., Delsol M., Ribot C. Ability of peripheral DXA measurements of the forearm to predict low axial bone mineral density at menopause. Osteoporos. Int. 2001;12(1):71-6.
  16. Fiter J., Nolla J.M., Gómez-Vaquero C., Martinez-Aguild D., Valverde J., Roig-Escofet D. A comparative study of computed digital absorptiometry and conventional dual-energy X-ray absorptiometry in postmenopausal women. Osteoporos. Int. 2001;12(7):565-69.
  17. Trivitayaratana W., Trivitayaratana P. The accuracy of bone mineral density at distal radius on non-forearm osteoporosis identification. J. Med. Assoc. Thai. 2001;84(4):566-71.

补充文件

附件文件
动作
1. JATS XML
下载

版权所有 © Bionika Media, 2016
##common.cookie##