Olaparib -modern approach to the treatment of BRCA-associated HER2-negative metastatic breast cancer. Clinical experience


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详细

Modern possibilities of molecular genetic diagnostics and advances in drug therapy for metastatic breast cancer (BC) have made it possible to personalize the treatment, thus improving its results. The use of PARP inhibitors in BRCA-associated BC is a priority option, which significantly improves the survival rates and quality of life of patients. The results of international studies are impressive, but there is still little experience with the use of PARP inhibitors in routine practice. This publication presents a clinical case of the successful use of olaparib (Linparza) in a young patient with metastatic HER2-negative BRCA-associated BC.

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作者简介

E. Lubennikova

N.N. Blokhin National Medical Research Center of Oncology

Email: lubennikova@yandex.ru
Moscow, Russia

L. Zhukova

A.S. Loginov Moscow Clinical Research Center

Moscow, Russia

O. Gordeeva

N.N. Blokhin National Medical Research Center of Oncology

Moscow, Russia

N. Drobot

N.N. Blokhin National Medical Research Center of Oncology

Moscow, Russia

A. Kuznetsov

Clinical Hospital MEDSI

Moscow, Russia

I. Ganshina

N.N. Blokhin National Medical Research Center of Oncology

Moscow, Russia

参考

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