Glomerular filtration rate in chronic heart failure patients. (Program for estimation of bacterial infection influence on kidney function in patients with chronic kidney failure)


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Abstract

Purpose. The estimation of influence of pneumococcal pneumonia on the glomerular filtration rate in patients with CHF.
Material and methods. During the 30 months, time course of indicants of renal function, including glomerular filtration rate (GFR) calculated by the MDRD formula, in 457 patients with chronic heart failure (CHF) admitted with community-acquired pneumococcal pneumonia were evaluated. Severity and risk of further deterioration of renal function were assessed by the RIFLE score, severity of pneumonia - by the Pneumonia severity index (PSI), severity of chronic heart failure - by the US score "warm / cold", comorbidity - by the Charlson index.
Results. Decrease of calculated GFR was recorded in all patients with CHF and pneumococcal pneumonia. The most significant decrease was observed in group of patients with deficiency of lean body mass, which initially had FC III-IV CHF, with a high index of comorbidity, and an false choice of first antibiotic.
Conclusion. Deterioration of renal filtration function is typical for CHF patients who have bacterial pneumonia; the most pronounced decrease of GFR is typical for the most severe patients.

References

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