INTERFERENCE PHASOMETRY OF THE LYMPHOCYTE NUCLEAR STRUCTURES AFTER KIDNEY TRANSPLANTATION
- Authors: Tsalman AY.1, Vatazin AV1, Vasilenko IA1, Metelin VB1, Vyshenskaya TV1
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- Issue: No 6 (2010)
- Pages: 43-47
- Section: Articles
- URL: https://journals.eco-vector.com/2075-3594/article/view/245934
- ID: 245934
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Abstract
Aim. Study of interference phasometry of the lymphocyte nuclear structures in early diagnosis of acute rejection of kidney transplant and monitoring of efficacy of subsequent immunosuppressive therapy.
Мethods. 36 patients with terminal renal failure who had undergone renal transplantation in years 2005 - 2008 (18 male, 18 female, mean age 42±9,5 years) were included into the study; 30 healthy volunteers (mean age 36±7,6 years) served as controls. Computed interference phasometry of the lymphocyte nuclear structures was performed.
Results. In terminal renal failure significant decrease of phase activity of nuclear structures of T-lymphocytes was detected. Elevation of this parameter was associated with development of acute rejection of kidney transplant.
Conclusion. Changes of phase activity of nuclear structures of T-lymphocytes can be used for early diagnosing of acute rejection of kidney transplant.
Мethods. 36 patients with terminal renal failure who had undergone renal transplantation in years 2005 - 2008 (18 male, 18 female, mean age 42±9,5 years) were included into the study; 30 healthy volunteers (mean age 36±7,6 years) served as controls. Computed interference phasometry of the lymphocyte nuclear structures was performed.
Results. In terminal renal failure significant decrease of phase activity of nuclear structures of T-lymphocytes was detected. Elevation of this parameter was associated with development of acute rejection of kidney transplant.
Conclusion. Changes of phase activity of nuclear structures of T-lymphocytes can be used for early diagnosing of acute rejection of kidney transplant.
References
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