Use of trihydric iron preparations in treatment of anemia in patients with pre-dialysis renal failure


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Abstract

Aim. Study of prevalence of anemia and iron deficiency in patients with chronic kidney disease (CKD) stage III - IV and assessment of trihydric iron preparations. Methods. 234 patients with chronic glomerulonephritis (primary and in systemic diseases) were included into the study; all of them had CKD III - IV stage. In 141 patients oral (Maltofer) and intravenous (Venofer) trihydric iron preparations were used.
Results. Anemia was revealed in 185 (84,2%) patients with CKD III - IV stages; prevalence of anemia increased according to glomerular filtration rate (GFR) decrease. In patients with systemic diseases anemia and iron deficiency were found more often even in mild decrease of GFR. Maltofer and Venofer were effective in anemia correction in CKD stage III - IV patients.
Conclusion. Anemia is frequent in CKD stage III - IV patients, especially in systemic diseases; in its correction trihydric iron preparations are effective

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