Membranoproliferative glomerulonephritis type II. Case, diagnosis and comments


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Аннотация

Membranoproliferative glomerulonephritis type II (dense deposit disease) is a rare glomerular disease with a hallmark sign of presence of electron-dense deposits within the glomerular basement membrane. The disease is caused with uncontrolled activation of alternative complement pathway. Some cases have a genetic origin. Childhood is a predominant age of the onset. The article presents a case report with comments

Авторлар туралы

A Tsygin

N Kartamysheva

D Shklyaev

L Leonova

P Povilaytite

Әдебиет тізімі

  1. Martinez-Barricarte R., Heurich M., Valdes-Canedo F. et al. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provaides insights into complement activation and regulation. J Clin Invest. 2010; 120(10): 3702-3712.
  2. Lachmann P.J. The amplification loop of complement pathways. Adv. Immunol. 2009; 104: 115-149.
  3. Суханов А.В., Румянцев А.Л., Цыгин А.Н.. Мембранопролиферативный гломерулонефрит 2-го типа (болезнь плотных подоцитов) с быстропрогрессирующим течением. Нефрология и диализ 2003; 5 (4): 399-400.
  4. Appel B. Gerald, Cook Terence H., Hageman G. et al. Membranoproliferative Glomerulonephritis Type II (Dense Deposit Disease): An Update. J Am Soc Nephrol. 2005; 16: 1392-1404.
  5. Smith R.J.H., Alexander J., Barlow P.N. Et al. New Approaches to the Treatment of Dense Deposit Disease. J Am Soc Nephrol. 2007; 18: 2447-2456.

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